ArticleSexually transmitted infections2019
Sexually transmitted infections during pregnancy and subsequent risk of stillbirth and infant mortality in Kenya: a prospective study.
Article in Sexually transmitted infections, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 9 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 9 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Prevalence of genital and anorectal chlamydia trachomatis in Kenya by risk groups: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Systematic review and meta-analysis of the global prevalence and infection risk factors of Trichomonas vaginalis.Parasite (Paris, France) · 2025Pooled it
- Vulvovaginal yeast infections during pregnancy and perinatal outcomes: systematic review and meta-analysis.BMC women's health · 2023Pooled it
- Prevalence of curable STIs and bacterial vaginosis during pregnancy in sub-Saharan Africa: a systematic review and meta-analysis.Sexually transmitted infections · 2022Pooled it
- Gonorrhoea: a systematic review of prevalence reporting globally.BMC infectious diseases · 2021Pooled it
- Trichomoniasis and adverse birth outcomes: a systematic review and meta-analysis.BJOG : an international journal of obstetrics and gynaecology · 2021Pooled it
- Adverse pregnancy and neonatal outcomes associated withSexually transmitted infections · 2021Pooled it
- Effect of Chlamydia trachomatis on adverse pregnancy outcomes: a meta-analysis.Archives of gynecology and obstetrics · 2020Pooled it
- The Association Between Vaginal Microbiota Dysbiosis, Bacterial Vaginosis, and Aerobic Vaginitis, and Adverse Pregnancy Outcomes of Women Living in Sub-Saharan Africa: A Systematic Review.Frontiers in public health · 2020Pooled it
- Youth-Friendly Sexual Health Services and Peer Support for Improved Sexual and Reproductive Health Outcomes Among Adolescents and Young Adults in South Africa: Results of a Factorial Randomized Controlled Trial.Sexually transmitted diseases · 2025Trial
- "It gives me the strength and courage to take care of myself": a qualitative exploration of experiences with STI testing among women who initiated PrEP during pregnancy in Western Kenya.Journal of the International AIDS Society · 2025Trial
- Effect of antenatalSexually transmitted infections · 2025Trial
- Identifying youth at high risk for sexually transmitted infections in community-based settings using a risk prediction tool: a validation study.BMC infectious diseases · 2021Trial
- High prevalence and incidence of curable sexually transmitted infections among young women using oral HIV pre-exposure prophylaxis in sub-Saharan Africa: results from the INSIGHT Cohort study.Sexually transmitted infections · 2026Observational
- Impact of antenatal screening for Chlamydia and Gonorrhea on pregnancy outcomes in South African women.BMC infectious diseases · 2026Article
- Prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae infections and associated risk factors among pregnant women and key populations in Kenya: A multi-centre cross-sectional study.PLOS global public health · 2026Article
- Article
- Sexual behaviors and self-reported sexually transmitted infections (STIs) among male and female youths in Nigeria.BMC infectious diseases · 2025Article
- Is screening and treating asymptomatic chlamydia and gonorrhoea among pregnant women cost-effective to prevent preterm birth and low birth weight in Botswana?Sexually transmitted infections · 2025Article
- Prevalence and associated factors of sexually transmitted infections among pregnant women attending antenatal care in public hospitals in Addis Ababa, Ethiopia.BMC infectious diseases · 2025Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesWe evaluated the relationship of sexually transmitted infections (STIs) and genital infections during pregnancy and subsequent risk for infant mortality and stillbirth.
methodsThis was a nested longitudinal analysis using data from a study of peripartum HIV acquisition in Kenya. In the parent study, HIV-uninfected women were enrolled during pregnancy and followed until 9 months postpartum. For this analysis, women who tested positive for HIV at any point, had a non-singleton pregnancy or a spontaneous abortion <20 weeks were excluded. At enrolment, laboratory methods were used to screen for bacterial vaginosis (BV), vaginal yeast,
resultsOverall, among 1221 women, 55% had STIs or genital infections detected: vaginal yeast (25%), BV (22%), TV (6%), CT (5%), NG (2%) and syphilis (1%). Among women with STIs/genital infections (n=592), 34% had symptoms. Overall, 19/1221 (2%) women experienced stillbirths. Among 1202 live births, 34 infant deaths occurred (incidence 4.0 deaths per 100 person-years, 95% CI 2.8 to 5.5). After adjustment for maternal age, education and study site, stillbirth was associated with maternal GUD (adjusted OR=9.19, 95% CI1.91 to 44.35, p=0.006). Maternal NG was associated with infant mortality (adjusted HR=3.83, 95% CI1.16 to 12.68, p=0.028); there was some evidence that maternal CT was associated with infant mortality. Stillbirth or infant mortality were not associated with other genital infections.
conclusionsSTIs and genital infections were common, frequently asymptomatic and some associated with stillbirth or infant mortality. Expediting diagnosis and treatment of STIs in pregnancy may improve infant outcomes.
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