Evidence map›Paper›PMID 30227690›Full record

ArticleBiomolecules2018

Lnc-EPB41-Protein Interactions Associated with Congenital Pouch Colon.

Sonal Gupta, Nidhi Gupta, Pradeep Tiwari, Saji Menon, Praveen Mathur, Shanker Lal Kothari, Sivaramaiah Nallapeta, Krishna Mohan Medicherla, Prashanth Suravajhala

Abstract read
In one paragraph

Article in Biomolecules, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Long Non-Coding RNAs in Insects.Animals : an open access journal from MDPI · 2021
    Review
  5. Is Pouch Specific to Colon and Not Ileum?Current pediatric reviews · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sonal GuptaDepartment of Biotechnology and Bioinformatics, Birla Institute of Scientific Research (BISR), Statue Circle, Jaipur 302021, India. slkothari28@gmail.com.ORCID 0000-0003-0379-1170
Nidhi GuptaDepartment of Biotechnology, IIS University, Mansarovar, Jaipur 302020, India. nidhinimesh@gmail.com.
Pradeep TiwariDepartment of Biotechnology and Bioinformatics, Birla Institute of Scientific Research (BISR), Statue Circle, Jaipur 302021, India. tiwari.pradeep30@gmail.com.
Saji MenonNanoTemper Technologies, World Trade Centre, Bengaluru 302017, India. menon.saji@gmail.com.
Praveen MathurDepartment of Paediatric Surgery, SMS Medical College, JLN Marg, Jaipur 302004, India. azadanitaashu@gmail.com.
Shanker Lal KothariDepartment of Biotechnology, Amity University Rajasthan, Kant Kalwar, Jaipur 303002, India. slkothari28@gmail.com.
Sivaramaiah NallapetaNanoTemper Technologies, World Trade Centre, Bengaluru 302017, India. myresearchbin@gmail.com.
Krishna Mohan MedicherlaDepartment of Biotechnology and Bioinformatics, Birla Institute of Scientific Research (BISR), Statue Circle, Jaipur 302021, India. kmohan@bisr.res.in.ORCID 0000-0001-7099-7721
Prashanth SuravajhalaDepartment of Biotechnology and Bioinformatics, Birla Institute of Scientific Research (BISR), Statue Circle, Jaipur 302021, India. prash@bisr.res.in.ORCID 0000-0002-8535-278X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital Pouch Colon (CPC) is a rare anorectal anomaly common to northwestern India, specifically Rajasthan. Despite efforts to understand the clinical genetic makeup of CPC, no attempt on identifying non-coding RNAs was done. We have earlier reported CPC's rare variants from whole exome sequencing (WES) across 18 affected samples in a total of 64 subjects. A Smith⁻Waterman algorithm was used to infer a couple of lncRNAs from WES samples of CPC with predictions from the Noncode database. Further screening and quantification using polymerase chain reaction (PCR), we ascertained interactions using Micro Scale Thermophoresis (MST). We report the role of

Indexed as

ColonCytoskeletal ProteinsHumansKinesinsMembrane ProteinsProtein BindingRNA, Long NoncodingCytoskeletal Proteinserythrocyte membrane band 4.1 proteinKIF13A protein, humanKinesinsMembrane ProteinsRNA, Long Noncodingcongenital pouch colonlong non coding RNAmicroscale thermophoresisprotein interactionwhole exome sequencing

Identifiers

PMID30227690
PMCPMC6163732

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.