ReviewHormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme2019
Catecholamine-Induced Cardiomyopathy in Pheochromocytoma: How to Manage a Rare Complication in a Rare Disease?
Review in Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.
- Effects of Music Therapy on Physiological Indicators and Subjective Comfort in Patients Undergoing Large Medical Imaging Examinations: A Systematic Review and Meta-Analysis.Journal of medical imaging and radiation oncology · 2026Pooled it
- Phaeochromocytoma Crisis Presenting As Inverted Takotsubo Cardiomyopathy in a Young Woman: A Successful Outcome.Cureus · 2026Article
- A 42-Year-Old Woman Presenting With Pheochromocytoma Multisystem Crisis Associated With Bilateral Pheochromocytomas Due to Multiple Endocrine Neoplasia Type 2A.The American journal of case reports · 2026Article
- When chest pain and troponin elevation aren't acute coronary syndrome: a cardiovascular case report of atypical pheochromocytoma.European heart journal. Case reports · 2026Article
- A Case Report of Myocardial Infarction Complicated With Blood Pressure Fluctuations Caused by Pheochromocytoma.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Prognostic factors for cardiovascular complications induced by catecholamines in pheochromocytomas and paragangliomas: a systematic review and meta-analysis.Hormones (Athens, Greece) · 2026Article
- Transient cavity dilatation during supine exercise bicycle stress testing: mechanistic insights.Echo research and practice · 2026Article
- A rare initial presentation of giant pheochromocytoma: a case report of acute pulmonary embolism complicated by catecholamine-induced cardiomyopathy.Frontiers in oncology · 2026Article
- Pheochromocytoma complicated with acute myocardial infarction and cerebral infarction: a case report.Frontiers in oncology · 2026Article
- Cardiomyopathies of endocrine origin: A state-of-the-art review.World journal of cardiology · 2025Review
- Acute myocardial injury induced by pheochromocytoma: a case report.BMC cardiovascular disorders · 2025Review
- High-Stakes Hormone: Vasopressin Use as a Last-Line Therapy for Shock in Pediatrics-A Narrative Review.Reports (MDPI) · 2025Review
- Article
- Pheochromocytoma-Induced Reversible Dilated Cardiomyopathy: A Case Report and Literature Review.Clinical case reports · 2025Article
- Housing temperature influences metabolic phenotype of heart failure with preserved ejection fraction in J vs N strain C57BL/6 mice.Molecular and cellular endocrinology · 2025Article
- An Incidental Finding of a Large Pheochromocytoma in an Asymptomatic Male: A Case Report.Cureus · 2024Article
- Giant Pheochromocytoma Resection Using Partial Cardiopulmonary Bypass and Blood Purification Therapy.JCEM case reports · 2024Article
- Is the peripheral microcirculation a window into the human coronary microvasculature?Journal of molecular and cellular cardiology · 2024Review
- Pheochromocytoma-induced diffuse alveolar hemorrhage after cholecystectomy: A case report and literature review.Heliyon · 2024Article
- Recurrent angina and cardiac ischaemia as a presentation of pheochromocytoma: a case report.European heart journal. Case reports · 2024Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Pheochromocytomas and paragangliomas (PHEOs) are rare neuroendocrine tumors. Clinical manifestations include different cardiovascular signs and symptoms, which are related to excessive secretion of catecholamines. Catecholamine-induced cardiomyopathy in PHEO (CICMPP) is a rare but dreaded complication of PHEO. Once patient is diagnosed with this condition, the prognosis is worse and a surgical risk is much higher than expected. This article focuses on how catecholamines affect the heart and the pathophysiologic mechanism of CICMPP. The cardiovascular responses to catecholamine depend mostly on which catecholamine is released as well as the amount of catecholamine that is released. The acute release of norepinephrine and epinephrine from PHEO increases heart rate, systemic vascular resistance, myocardial contractility, and reduces venous compliance. The excessive adrenergic stimulation by catecholamine results in severe vasoconstriction and coronary vasospasm, myocardial ischemia, and subsequently damage, and necrosis. Chronically elevated catecholamine levels lead to significant desensitization of cardiac β-adrenoceptors. The increased levels of the enzyme β-adrenoceptors kinase (βARK) in the heart seems to mediate these biochemical and physiological changes that are consistently correlated with attenuated responsiveness to catecholamine stimulation. Through these mechanisms different types of cardiomyopathy (CMP) can be formed. This review discusses extensively the 3 types of cardiomyopathies that can be present in a PHEO patient. It also provides the clinical presentation and diagnostic and therapeutic algorithm in managing patients with CICMPP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.