ArticlePloS one2018
Age dependent normative data of vertical and horizontal reflexive saccades.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- Portable eye-tracking as a reliable assessment of oculomotor, cognitive and reaction time function: Normative data for 18-45 year old.PloS one · 2021Trial
- Oculomotor Profiles in Children Wearing Different Myopia Control Lenses: A Real-World Eye Tracking Study.Vision (Basel, Switzerland) · 2026Article
- Global Rather Than Vertical-Selective Saccadic Abnormalities in Progressive Supranuclear Palsy.Annals of clinical and translational neurology · 2026Article
- Ophthalmic and Oculomotor Characteristics in Ataxia-Telangiectasia: A Clinical Cohort Study using Video-Oculography.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Normative Values for Prosaccade and Antisaccade Eye Movements in Adolescents Using a New Saccadometry Test.Journal of the American Academy of Audiology · 2026Article
- Diagnostic value of saccades in mild cognitive impairment: a community-based study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- An Evaluation of Test-Retest Reliability of the Saccadometry Test.Journal of the American Academy of Audiology · 2025Article
- Lawful kinematics link eye movements to the limits of high-speed perception.Nature communications · 2025Article
- Oculomotor, vestibular, reaction time, and cognitive (OVRT-C) responses in 7- to 17-year-old children.Experimental brain research · 2025Article
- Establishment of Normal Values for Objective Evaluation of Ocular Movements Using Videonystagmography.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Oculomotor Impairments in Children After Posterior Fossa Tumors Treatment.Cerebellum (London, England) · 2024Article
- The Effect of Stimulus Contrast and Spatial Position on Saccadic Eye Movement Parameters.Vision (Basel, Switzerland) · 2023Article
- Biologia Futura: does the aging process contribute to the relativity of time?Biologia futura · 2023Review
- The Saccade Main Sequence in Patients With Retinitis Pigmentosa and Advanced Age-Related Macular Degeneration.Investigative ophthalmology & visual science · 2023Article
- Clinical Saccadometry: Establishing Evaluative Standards Using a Simplified Video Oculography Protocol in the Adult Population.Journal of the American Academy of Audiology · 2023Article
- Retinal thinning in phenylketonuria and Gaucher disease type 3.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- Ocular-following responses in school-age children.PloS one · 2022Article
- Uncovering bilateral vestibulopathy in patients with SANDO syndrome caused by mutations in POLG gene: a case series.Journal of neurology · 2021Article
- Freezing of saccades in dopa-responsive parkinsonian syndrome.American journal of ophthalmology case reports · 2021Article
- Proof of Concept of Novel Visuo-Spatial-Motor Fall Prevention Training for Old People.Geriatrics (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThere is some controversy whether or not saccades change with age. This cross-sectional study aims to clarify the characteristics of reflexive saccades at various ages to establish a normative cohort in a standardized set-up. Second objective is to investigate the feasibility of saccadometry in daily ophthalmological practice.
methodsOne hundred healthy participants aged between 6 and 76 years underwent an ophthalmologic examination and saccadometry, using an infrared video-oculography device, sampling at 220 Hz. The reflexive saccades were evoked in four directions and three target displacements each (5°/15°/30° horizontally and of 5°/10°/20° vertically). Saccadic peak velocity, gain (amplitude/target displacement) and latency were measured.
resultsMean peak velocity of saccades was 213°/s (± 29°/s), 352°/s (± 50°/s) and 455°/s (± 67°/s) to a target position 5°, 15°and 30° horizontally, respectively, and 208°/s (± 36°/s), 303°/s (± 50°/s) and 391°/s (± 71°/s) to a target position 5°, 10° and 20° vertically. The association between peak velocity and eccentricity proved to be present at any age in all four directions. We found no relevant effect of age on peak velocity, gain and latency in a fitted linear mixed model. However, latency becomes shorter during childhood and adolescence, while in adulthood it is relatively stable with a slight trend to increase in the elderly. Saccades are more precise when the target displacement is small. Isometric saccades are most common, followed by hypometric ones. All children and elderly were able to perform good quality saccadometry in a recording time of approximately 10 minutes.
conclusionThe presented data may serve as normative control for further studies using such a video-oculography device for saccadometry. The means of peak velocity and the gain can be used independently from age respecting the target displacement. Latency is susceptible to age.
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