ReviewThe British journal of radiology2019
AGuIX
Registry-linked trialAbstract readReview
In one paragraph
Review in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03818386 (Radiotherapy of Multiple Brain Metastases Using AGuIX® Gadolinium-chelated Polysiloxane Based Nanoparticles), which is not on this map. Cited by 99 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Radiotherapy of Multiple Brain Metastases Using AGuIX® Gadolinium-chelated Polysiloxane Based Nanoparticles: a Prospective Randomized Phase II Clinical Trial.
Who cites it
99 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Golden era of radiosensitizers.Frontiers in veterinary science · 2024Pooled it
- Chemical vs Physical Radioenhancement from TiONano letters · 2025Trial
- Quantifying gadolinium-based nanoparticle uptake distributions in brain metastases via magnetic resonance imaging.Scientific reports · 2024Trial
- Proof of Concept of the Radiosensitizing Effect of Gadolinium Oxide Nanoparticles in Cell Spheroids and a Tumor-Implanted Murine Model of Chondrosarcoma.International journal of nanomedicine · 2022Trial
- Redox-immune modulating gadolinium vanadate based nanozymes for osteoarthritis therapy.Materials today. Bio · 2026Article
- Activatable MRI nanoprobes for tumor and immune microenvironment imaging: biological mechanisms and translational implications.Materials today. Bio · 2026Review
- Nano-Metal Hydrogen Therapy Targeting Immune Cells Drives Synergistic Anti-Tumor Effects.Molecules (Basel, Switzerland) · 2026Review
- Applications of Bioinorganic Nano-Based Delivery Systems-Diagnostics and Therapeutics.Drug development research · 2026Review
- Multifunctional Nano-Contrast Agent Carriers: From Traditional Platforms to Next-Generation Theranostic Applications in Molecular Imaging.Biomedicines · 2026Review
- Beyond apoptosis: nanomedicine enabled reprogramming of tumor cell death for next-generation radiosensitization.Journal of nanobiotechnology · 2026Review
- Clinical translation and landscape of stimuli-responsive nanomedicines and microscale therapeutics.Chemical Society reviews · 2026Review
- Nanomaterials reshaping cancer radiotherapy: Radiosensitization mechanisms, delivery and theranostic platforms, multimodal synergy, and clinical translation strategies.Materials today. Bio · 2026Review
- Gadolinium-Doped Iron Oxide Nanoparticles Enhance Radiosensitivity in Melanoma Models Associated with Metabolic Dysfunction.Pharmaceutics · 2026Article
- Magnetic resonance imaging-based biodistribution of theranostic AGuIX nanoparticles in the NANORAD 2 clinical trial for brain metastases.Journal of neuro-oncology · 2026Article
- Gadolinium Nanoparticles: Emerging Platforms Beyond Imaging for Drug Delivery and Theranostics.Pharmaceutics · 2026Review
- Metal Nanoparticles as Sensitizers in Energy-Based Therapies for Lung Cancer: From Mechanistic Insights to Clinical Translation.International journal of nanomedicine · 2026Review
- Lanthanide Nanotheranostics in Radiotherapy.International journal of molecular sciences · 2025Review
- A Modular Supramolecular Peptide Platform Reveals Atomic-Number-Dependent Mechanisms Driving Radioenhancement.ACS nano · 2025Article
- Hybrid biomaterials-based radiosensitizers: Preparations and their applications in enhancing tumor radiotherapy.Materials today. Bio · 2025Article
- Second-Generation Gadolinium-Bismuth Ultrasmall Nanoparticles Amplify the Effects of Clinical Radiation Therapy and Provide Clinical Magnetic Resonance Imaging Contrast.International journal of radiation oncology, biology, physics · 2025Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
48 authors.
François LuxNH TherAguix SAS, Villeurbanne, France.
Vu Long TranUniv Lyon Université Claude Bernard Lyon 1, CNRS, Institut Lumière Matière, LYON, France.
Eloïse ThomasUniv Lyon Université Claude Bernard Lyon 1, CNRS, Institut Lumière Matière, LYON, France.
Sandrine DufortNH TherAguix SAS, Villeurbanne, France.
Fabien RossettiUniv Lyon Université Claude Bernard Lyon 1, CNRS, Institut Lumière Matière, LYON, France.
Matteo MartiniUniv Lyon Université Claude Bernard Lyon 1, CNRS, Institut Lumière Matière, LYON, France.
Charles TruilletImagerie Moléculaire In Vivo, Inserm, CEA, CNRS, Univ Paris Sud, Université Paris Saclay - Service Hospitalier Frédéric Joliot, Orsay, France.
Tristan DoussineauNH TherAguix SAS, Villeurbanne, France.
Guillaume BortUniv Lyon Université Claude Bernard Lyon 1, CNRS, Institut Lumière Matière, LYON, France.
Franck DenatInstitut de Chimie Moléculaire, Université de Bourgogne, Dijon, France.
Frédéric BoschettiCheMatech, Faculté des Sciences Mirande, Dijon, France.
Goran AngelovskiMR Neuroimaging Agents, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany.
Alexandre DetappeDana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, MA, USA.
Yannick CrémillieuxCentre de Résonance Magnétique des Systèmes Biologiques, CNRS UMR, Université Bordeaux, Bordeaux, France.
Nathalie MignetChimie ParisTech, PSL Research University, Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS), Paris, France.
Bich-Thuy DoanChimie ParisTech, PSL Research University, Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS), Paris, France.
Benoit LarratNeuroSpin, CEA Saclay, Gif-sur-Yvette, France.
Sébastien MeriauxNeuroSpin, CEA Saclay, Gif-sur-Yvette, France.
Emmanuel BarbierINSERM, Univ. Grenoble Alpes, Grenoble Institut des Neurosciences , Grenoble, France.
Stéphane RouxInstitut UTINAM, UMR CNRS 6213-Université de Bourgogne Franche-Comté, Besançon, France.
Peter FriesClinic of Diagnostic and Interventional Radiology, Saarland University Medical Center, Homburg/Saar, Germany.
Andreas MüllerClinic of Diagnostic and Interventional Radiology, Saarland University Medical Center, Homburg/Saar, Germany.
Marie-Caline AbadjianDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Carolyn AndersonDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Emmanuelle Canet-SoulasUniv Lyon, CarMeN Laboratory Institut National de la Santé et de la Recherche Médicale U1060,INRA U1397, Université Lyon 1, INSA Lyon, Oullins, France.
Penelope BouziotisInstitute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Center forScientific Research "Demokritos", Aghia Paraskevi, Athens, Greece.
Muriel Barberi-HeyobUniversité de Lorraine, CNRS, CRAN, Nancy, France.
Céline FrochotLaboratoire Réactions et Génie des Procédés, UMR, Université de Lorraine-CNRS, Nancy, France.
Camille VerryRadiotherapy department, CHU de Grenoble, Grenoble cedex 9, France.
Jacques BalossoRadiotherapy department, CHU de Grenoble, Grenoble cedex 9, France.
Michael EvansDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, USA.
Jacqueline Sidi-BoumedineUNIV Lyon - Université Claude Bernard Lyon 1, Villeurbanne, France.
Marc JanierUNIV Lyon - Université Claude Bernard Lyon 1, Villeurbanne, France.
Karl ButterworthCentre for Cancer Research and Cell Biology Queen's University Belfast,, Belfast BT9 7AE, UK.
Stephen McMahonCentre for Cancer Research and Cell Biology Queen's University Belfast,, Belfast BT9 7AE, UK.
Kevin PriseCentre for Cancer Research and Cell Biology Queen's University Belfast,, Belfast BT9 7AE, UK.
Marie-Thérèse AloyIPNL, PRISME, Laboratoire de Radiobiologie Cellulaire et Moléculaire, Faculté de Médecine Lyon-Sud, Université Lyon 1; Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, Pierre-Bénite, France.
Dominique ArdailIPNL, PRISME, Laboratoire de Radiobiologie Cellulaire et Moléculaire, Faculté de Médecine Lyon-Sud, Université Lyon 1; Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, Pierre-Bénite, France.
Claire Rodriguez-LafrasseIPNL, PRISME, Laboratoire de Radiobiologie Cellulaire et Moléculaire, Faculté de Médecine Lyon-Sud, Université Lyon 1; Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, Pierre-Bénite, France.
Erika PorcelISMO UMR, Université Paris Saclay, Université Paris Sud, CNRS, Orsay cedex, France.
Sandrine LacombeISMO UMR, Université Paris Saclay, Université Paris Sud, CNRS, Orsay cedex, France.
Ross BerbecoDana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, MA, USA.
Awatef AllouchCell death and Aging team, Gustave Roussy, rue Edouard Vaillant, Villejuif, France.
Jean-Luc PerfettiniCell death and Aging team, Gustave Roussy, rue Edouard Vaillant, Villejuif, France.
Cyrus ChargariFrench Military Health Academy, Ecole du Val-de-Grâce, Paris, France.
Eric DeutschRadiotherapy Department, Gustave Roussy, Villejuif, France.
Géraldine Le DucNH TherAguix SAS, Villeurbanne, France.
Olivier TillementNH TherAguix SAS, Villeurbanne, France.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AGuIX
Indexed as
AnimalsBrain NeoplasmsForecastingGadoliniumHead and Neck NeoplasmsHumansMelanomaMiceNanoparticlesRadiation-Sensitizing AgentsTheranostic NanomedicineGadoliniumRadiation-Sensitizing Agents
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
NCT03818386ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.