Evidence map›Paper›PMID 30226184›Full record

ArticleEmerging infectious diseases2018

Rapid Spread of Pneumococcal Nonvaccine Serotype 7C Previously Associated with Vaccine Serotype 19F, England and Wales.

Ashley Makwana, Shamez N Ladhani, Georgia Kapatai, Ella Campion, Norman K Fry, Carmen Sheppard

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Serotype Distribution ofInfection and drug resistance · 2021
    Article
  6. Early Signals of Vaccine-driven Perturbation Seen in Pneumococcal Carriage Population Genomic Data.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  7. Article
  8. The Genomics ofGenes · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ashley Makwana
Shamez N Ladhani
Georgia Kapatai
Ella Campion
Norman K Fry
Carmen Sheppard

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We observed a sudden and rapid increase in rare invasive pneumococcal disease serotype 7C, from an annual average of 3 cases during 2000-01 through 2015-16 to 29 cases in 2016-17. The increase was caused almost entirely by clonal expansion of sequence type 177, previously associated with vaccine serotype 19F.

Indexed as

AdolescentAgedAged, 80 and overAnti-Bacterial AgentsChildDrug Resistance, BacterialEnglandFemaleGenome, BacterialHumansMaleMicrobial Sensitivity TestsMiddle AgedPhylogenyPneumococcal InfectionsPneumococcal VaccinesAnti-Bacterial AgentsPneumococcal VaccinesVaccines, Conjugatebacteriacapsular switchingEnglandinvasive pneumococcal diseasepneumococcal conjugate vaccinesreplacement diseasesequence typeserotypeserotype 7CST177Streptococcus pneumoniaeUnited KingdomWales

Identifiers

PMID30226184
PMCPMC6154145

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.