Evidence map›Paper›PMID 30226162›Full record

ArticleEmerging infectious diseases2018

Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden.

Johan Kaarme, Hilde Riedel, Wesley Schaal, Hong Yin, Tryggve Nevéus, Åsa Melhus

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  14. Clinical Microbiology in the Intensive Care Unit: Time for Intensivists to Rejuvenate this Lost Art.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Johan Kaarme
Hilde Riedel
Wesley Schaal
Hong Yin
Tryggve Nevéus
Åsa Melhus

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

By collecting and analyzing diapers, we identified a >6-fold increase in carriage of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae for healthy preschool children in Sweden (p<0.0001). For 6 of the 50 participating preschools, the carriage rate was >40%. We analyzed samples from 334 children and found 56 containing >1 ESBL producer. The prevalence in the study population increased from 2.6% in 2010 to 16.8% in 2016 (p<0.0001), and for 6 of the 50 participating preschools, the carriage rate was >40%. Furthermore, 58% of the ESBL producers were multidrug resistant, and transmission of ESBL-producing and non-ESBL-producing strains was observed at several of the preschools. Toddlers appear to be major carriers of ESBL producers in Sweden.

Indexed as

Carrier StateEnterobacteriaceaeAnti-Bacterial Agentsbeta-LactamasesChild, PreschoolEnterobacteriaceae InfectionsFemaleFollow-Up StudiesGenome, BacterialHumansInfantMaleMicrobial Sensitivity TestsPopulation SurveillancePrevalenceSwedenAnti-Bacterial Agentsbeta-LactamasesAmpCantimicrobial resistancebacteriacarriage ratescephalosporin resistanceenteric infectionsEnterobacteriaceaeESBLsextended-spectrum β-lactamaseshealthy preschool childrenpreschool childrenrespiratory infectionsSwedenwhole-genome sequencing

Identifiers

PMID30226162
PMCPMC6154144

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.