Evidence map›Paper›PMID 30226161›Full record

ArticleEmerging infectious diseases2018

Influenza Transmission Dynamics in Urban Households, Managua, Nicaragua, 2012-2014.

Aubree Gordon, Tim K Tsang, Benjamin J Cowling, Guillermina Kuan, Sergio Ojeda, Nery Sanchez, Lionel Gresh, Roger Lopez, Angel Balmaseda, Eva Harris

Open access · diamondAbstract readHistorical Article
In one paragraph

Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Nicaraguan Pediatric Influenza Cohort Study, 2011-2019: Influenza Incidence, Seasonality, and Transmission.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  10. The Spectrum of Influenza in Children.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Obesity Is Associated With Increased Susceptibility to Influenza A (H1N1pdm) but Not H3N2 Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  15. Article
  16. Influenza in Children.Cold Spring Harbor perspectives in medicine · 2021
    Review
  17. Association Between the Respiratory Microbiome and Susceptibility to Influenza Virus Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  18. Review
  19. Article
  20. Pre-existing Antineuraminidase Antibodies Are Associated With Shortened Duration of Influenza A(H1N1)pdm Virus Shedding and Illness in Naturally Infected Adults.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Aubree Gordon
Tim K Tsang
Benjamin J Cowling
Guillermina Kuan
Sergio Ojeda
Nery Sanchez
Lionel Gresh
Roger Lopez
Angel Balmaseda
Eva Harris
University of California, Berkeley · USUniversity of Hong Kong · HKUniversity of Michigan–Ann Arbor · USSustainable Sciences Institute · US

Funding

Understanding and controlling antibiotic resistanceU54GM088558 · NIGMS · HARVARD SCHOOL OF PUBLIC HEALTH · PI HANAGE, WILLIAM · 2009 to 2018
$26.4M
Epidemiology, transmission, and phylogenetics of influenza in a tropical countryU01AI088654 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI GORDON, AUBREE L, HARRIS, EVA · 2010 to 2014
$3.2M
Epidemiology and Transmission of Influenza in NicaraguaK02TW009483 · FIC · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GORDON, AUBREE L · 2012 to 2016
$419k
FIC NIH HHS K02 TW009483NIAID NIH HHS HHSN272201400006CNIAID NIH HHS U01 AI088654NIGMS NIH HHS U54 GM088558
6 · The paper itself

Abstract

During August 2012-November 2014, we conducted a case ascertainment study to investigate household transmission of influenza virus in Managua, Nicaragua. We collected up to 5 respiratory swab samples from each of 536 household contacts of 133 influenza virus-infected persons and assessed for evidence of influenza virus transmission. The overall risk for influenza virus infection of household contacts was 15.7% (95% CI 12.7%-19.0%). Oseltamivir treatment of index patients did not appear to reduce household transmission. The mean serial interval for within-household transmission was 3.1 (95% CI 1.6-8.4) days. We found the transmissibility of influenza B virus to be higher than that of influenza A virus among children. Compared with households with <4 household contacts, those with >4 household contacts appeared to have a reduced risk for infection. Further research is needed to model household influenza virus transmission and design interventions for these settings.

Indexed as

Family CharacteristicsUrban HealthAdolescentAge FactorsChildChild, PreschoolFemaleHistory, 21st CenturyHumansInfantInfant, NewbornInfluenza A virusInfluenza, HumanMaleNicaraguaPopulation SurveillanceageH1N1H3N2householdhousehold contactshousehold transmissioninfluenzainfluenza Ainfluenza BManaguaNicaraguaoseltamivirrespiratory infectionsrisk for infectionserial intervaltransmissionvaccinationviruses

Identifiers

PMID30226161
PMCPMC6154158
OpenAlexW2893429077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.