Evidence map›Paper›PMID 30226142›Full record

ArticleThe American journal of tropical medicine and hygiene2018

Case Report: Ivermectin and Albendazole Plasma Concentrations in a Patient with Disseminated Strongyloidiasis on Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Therapy.

Carl Boodman, Yashpal S Chhonker, Daryl J Murry, Allison Mah, Jennifer Grant, Theodore Steiner, Michael Libman, Cesilia Nishi, Marthe Charles

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Carl BoodmanDepartment of Medicine, University of British Columbia, Vancouver, Canada.
Yashpal S ChhonkerUniversity of Nebraska Medical Centre, Omaha, Nebraska.
Daryl J MurryUniversity of Nebraska Medical Centre, Omaha, Nebraska.
Allison MahDepartment of Medicine, University of British Columbia, Vancouver, Canada.
Jennifer GrantDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
Theodore SteinerDepartment of Medicine, University of British Columbia, Vancouver, Canada.
Michael LibmanJ. D. MacLean Centre for Tropical Diseases, McGill University, Montreal, Canada.
Cesilia NishiDepartment of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada.
Marthe CharlesDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
University of British Columbia · CAUniversity of Nebraska Medical Center · USMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disseminated strongyloidiasis is often fatal, despite treatment with oral albendazole and parenteral ivermectin (IVM). Here, we report elevated plasma IVM and albendazole sulfoxide concentrations in the context of extracorporeal membrane oxygenation and continuous renal replacement therapy in a patient with disseminated strongyloidiasis treated with subcutaneous IVM and nasogastric albenzadole. Despite elevated drug plasma concentrations, live filariform larvae were detected in endotracheal aspirates after 2 weeks of treatment.

Indexed as

Extracorporeal Membrane OxygenationRenal DialysisAlbendazoleAnimalsAnthelminticsHumansIvermectinLarvaMaleMiddle AgedStrongyloides stercoralisStrongyloidiasisAlbendazoleAnthelminticsIvermectin

Identifiers

PMID30226142
PMCPMC6221216
OpenAlexW2890711486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.