Evidence map›Paper›PMID 30226141›Full record

ArticleThe American journal of tropical medicine and hygiene2018

Surveillance for Flaviviruses Near the Mexico-U.S. Border: Co-circulation of Dengue Virus Serotypes 1, 2, and 3 and West Nile Virus in Tamaulipas, Northern Mexico, 2014-2016.

S Viridiana Laredo-Tiscareño, Javier A Garza-Hernandez, Ma Isabel Salazar, Erick J De Luna-Santillana, Chandra S Tangudu, Rosa C Cetina-Trejo, Gloria L Doria-Cobos, Santos Daniel Carmona-Aguirre, Julian E Garcia-Rejon, Carlos Machain-Williams and 2 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Serological Evidence of Flavivirus Infection Among Mothers of Newborns in El Paso, Texas.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

S Viridiana Laredo-TiscareñoDepartment of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa.
Javier A Garza-HernandezLaboratorio Entomología Médica, Instituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Ciudad Juárez, Chihuahua, México.
Ma Isabel SalazarLaboratorio de Virología e Inmunovirología, Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de México, Mexico.
Erick J De Luna-SantillanaLaboratorio Medicina de la Conservación, Centro de Biotecnología Genómica del Instituto Politécnico Nacional, Reynosa, Tamaulipas, México.
Chandra S TanguduDepartment of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa.
Rosa C Cetina-TrejoLaboratorio de Arbovirología, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi," Universidad Autónoma de Yucatán, Mérida, México.
Gloria L Doria-CobosDepartamento de Epidemiología de la Cuarta Jurisdicción Sanitaria, Secretaria de Salud, Reynosa, Tamaulipas, México.
Santos Daniel Carmona-AguirreSecretaría de Salud del Estado de Tamaulipas, Dirección de Epidemiología, Ciudad Victoria, Tamaulipas, México.
Julian E Garcia-RejonLaboratorio de Arbovirología, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi," Universidad Autónoma de Yucatán, Mérida, México.
Carlos Machain-WilliamsLaboratorio de Arbovirología, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi," Universidad Autónoma de Yucatán, Mérida, México.
Bradley J BlitvichDepartment of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa.
Mario Alberto Rodríguez PérezLaboratorio de Biomedicina Molecular, Centro de Biotecnología Genómica del Instituto Politécnico Nacional, Reynosa, Tamaulipas, México.

Funding

Phenotypic characterization of T’Ho virus and the development of tools for its serologic diagnosisR03AI167042 · NIAID · IOWA STATE UNIVERSITY · PI BLITVICH, BRADLEY J · 2022 to 2023
$153k
NIAID NIH HHS R03 AI167042
6 · The paper itself

Abstract

A clinical, serological, and molecular investigation was performed to determine the presence of dengue virus (DENV) and other flaviviruses among residents of the city of Reynosa, Tamaulipas, on the Mexico-U.S. border in 2014-2016. The sample population consisted of 2,355 patients with suspected dengue, in addition to 346 asymptomatic individuals recruited during a household-based epidemiological investigation designed to identify flavivirus seroconversions. Sera were collected from patients with suspected dengue in the acute phase of illness and from asymptomatic individuals at enrollment and every 5-7 months for 19 months. Sera from suspected dengue patients were tested for DENV antigen by enzyme-linked immunosorbent assay (ELISA), and select antigen-positive sera were further tested using a serotype-specific, quantitative reverse transcription-polymerase chain reaction. Sera from the household cohort were tested for flavivirus-reactive antibodies by immunoglobulin (Ig) M and IgG ELISAs using DENV antigen. A total of 418 (17.7%) patients with suspected dengue had laboratory-confirmed DENV infections, including 82 patients who were positive for DENV RNA. The most frequently detected serotype was DENV-1 (61 patients), followed by DENV-2 (16 patients) and DENV-3 (five patients). A total of 217 (62.7%) asymptomatic individuals had flavivirus-reactive antibodies at enrollment, and nine flavivirus-naïve individuals seroconverted. Sera from a subset of dengue patients and household participants, including all those who seroconverted, were further tested by plaque reduction neutralization test, resulting in the detection of antibodies to DENV-1, DENV-2, and West Nile virus. In summary, we provide evidence for the co-circulation of multiple flaviviruses in Reynosa, Tamaulipas, on the Mexico-U.S. border.

Indexed as

SerogroupAdolescentAdultAgedAged, 80 and overAntibodies, ViralAsymptomatic InfectionsChildChild, PreschoolCohort StudiesDengueDengue VirusEnzyme-Linked Immunosorbent AssayFamily CharacteristicsFemaleFlavivirusAntibodies, Viral

Identifiers

PMID30226141
PMCPMC6221250

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.