ArticleInfection control and hospital epidemiology2018
Effectiveness of ultraviolet disinfection in reducing hospital-acquired Clostridium difficile and vancomycin-resistant Enterococcus on a bone marrow transplant unit.
Article in Infection control and hospital epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Impact of environmental hygiene interventions on healthcare-associated infections and patient colonization: a systematic review.Antimicrobial resistance and infection control · 2022Pooled it
- Systematic review on use, cost and clinical efficacy of automated decontamination devices.Antimicrobial resistance and infection control · 2021Pooled it
- Role of pulsed-xenon ultraviolet light in reducing healthcare-associated infections: a systematic review and meta-analysis.Epidemiology and infection · 2020Pooled it
- Ultraviolet-C Light Evaluation as Adjunct Disinfection to Remove Multidrug-Resistant Organisms.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Trial
- Efficacy of UV-C devices in Clostridioides difficile environmental decontamination in a hospital setting: a before-after study.BMC infectious diseases · 2026Article
- Article
- Importance of Ultraviolet-C (UV-C) Emitter Configuration for Clostridioides difficile Attenuation.Cureus · 2024Article
- Minimizing the risk ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- The in situ efficacy of whole room disinfection devices: a literature review with practical recommendations for implementation.Antimicrobial resistance and infection control · 2022Review
- Hospital surface disinfection using ultraviolet germicidal irradiation technology: A review.Healthcare technology letters · 2022Review
- Clostridioides difficile-Associated Diarrhea: Infection Prevention Unknowns and Evolving Risk Reduction Strategies.Current infectious disease reports · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
objectiveTo determine the effectiveness of ultraviolet (UV) environmental disinfection system on rates of hospital-acquired vancomycin-resistant enterococcus (VRE) and Clostridium difficile.
designUsing active surveillance and an interrupted time-series design, hospital-acquired acquisition of VRE and C. difficile on a bone marrow transplant (BMT) unit were examined before and after implementation of terminal disinfection with UV on all rooms regardless of isolation status of patients. The main outcomes were hospital-based acquisition measured through (1) active surveillance: admission, weekly, and discharge screening for VRE and toxigenic C. difficile (TCD) and (2) clinical surveillance: incidence of VRE and CDI on the unit.
settingBone marrow transplant unit at a tertiary-care cancer center.ParticipantsStem cell transplant (SCT) recipients.InterventionTerminal disinfection of all rooms with UV regardless of isolation status of patients.
resultsDuring the 20-month study period, 579 patients had 704 admissions to the BMT unit, and 2,160 surveillance tests were performed. No change in level or trend in the incidence of VRE (trend incidence rate ratio [IRR], 0.96; 95% confidence interval [CI], 0.81-1.14; level IRR, 1.34; 95% CI, 0.37-1.18) or C. difficile (trend IRR, 1.08; 95% CI, 0.89-1.31; level IRR, 0.51; 95% CI, 0.13-2.11) was observed after the intervention.
conclusionsUtilization of UV disinfection to supplement routine terminal cleaning of rooms was not effective in reducing hospital-acquired VRE and C. difficile among SCT recipients.
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