Evidence map›Paper›PMID 30225906›Full record

ArticleDevelopmental dynamics : an official publication of the American Association of Anatomists2018

Expression analysis of limb element markers during mouse embryonic development.

Alexandra Rafipay, Amanda L R Berg, Lynda Erskine, Neil Vargesson

Abstract read
In one paragraph

Article in Developmental dynamics : an official publication of the American Association of Anatomists, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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  5. Biallelic variants in ADAMTS15 cause a novel form of distal arthrogryposis.Genetics in medicine : official journal of the American College of Medical Genetics · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexandra RafipaySchool of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen.
Amanda L R BergSchool of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen.
Lynda ErskineSchool of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen.
Neil VargessonSchool of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen.

Funding

BBSRC EastBIO Doctoral Training Programme. Year 2012
6 · The paper itself

Abstract

backgroundWhile data regarding expression of limb element and tissue markers during normal mouse limb development exist, few studies show expression patterns in upper and lower limbs throughout key limb development stages. A comparison to normal developmental events is essential when analyzing development of the limb in mutant mice models.

resultsExpression patterns of the joint marker Gdf5, tendon and ligament marker Scleraxis, early muscle marker MyoD1, and blood vessel marker Cadherin5 (Cdh5) are presented during the most active phases of embryonic mouse limb patterning. Anti-neurofilament staining of developing nerves in the fore- and hindlimbs and cartilage formation and progression also are described.

conclusionsThis study demonstrates and describes a range of key morphological markers and methods that together can be used to assess normal and abnormal limb development. Developmental Dynamics 247:1217-1226, 2018. © 2018 The Authors. Developmental Dynamics published by Wiley Periodicals, Inc. on behalf of American Association of Anatomists.

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsAntigens, CDBiomarkersBody PatterningCadherin 5CadherinsChondrogenesisEmbryo, MammalianEmbryonic DevelopmentExtremitiesGrowth Differentiation Factor 5Intermediate FilamentsMiceMyoD ProteinAntigens, CDBiomarkersCadherin 5CadherinsGdf5 protein, mouseGrowth Differentiation Factor 5MyoD1 myogenic differentiation proteinMyoD ProteinAlcian Blue/Alizarin RedcartilageforelimbGene expressionhindlimbjointlimb developmentmusclenervetendonvascular

Identifiers

PMID30225906
PMCPMC6282987

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.