The epicardial adipose inflammatory triad: coronary atherosclerosis, atrial fibrillation, and heart failure with a preserved ejection fraction.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

1. Cardiovascular Disease in the Context of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Comprehensive Narrative Review.International journal of molecular sciences · 2025
   Pooled it
2. Bariatric surgery and cardiovascular disease: a systematic review and meta-analysis.European heart journal · 2022
   Pooled it
3. Near-universal prevalence of central adiposity in heart failure with preserved ejection fraction: the PARAGON-HF trial.European heart journal · 2025
   Trial
4. Left Atrial Remodeling and Functional Maladaptations in Obesity: An Invasive Pressure-Volume Analysis.Circulation. Heart failure · 2026
   Article
5. The Relationship Between the Systemic Immune Inflammatory Index and Atrial Fibrillation in Heart Failure with Preserved Ejection Fraction.The Eurasian journal of medicine · 2026
   Article
6. Metabolic Dysfunction-Associated Steatotic Liver Disease as a Systemic Driver of Heart Failure With Preserved Ejection Fraction: Mechanistic Insights and Emerging Therapeutic Perspectives.Reviews in cardiovascular medicine · 2026
   Review
7. Adipose Tissue Circadian Dysregulation Beyond BMI: Implications for Cardiometabolic Risk and Cardiovascular Disease.Life (Basel, Switzerland) · 2026
   Review
8. Association of obesity-metabolic indices with heart failure in patients with coronary artery disease: a multicenter retrospective observational study.Frontiers in endocrinology · 2026
   Observational
9. Joint assessment of white blood cell-to-HDL cholesterol ratio and waist-to-height-hemoglobin A1c for cardiometabolic multimorbidity risk: a prospective cohort study and cross-sectional study.Frontiers in nutrition · 2026
   Article
10. Predictive value of left atrial diameter and epicardial adipose tissue in sleep apnea and heart failure with preserved ejection fraction.Frontiers in cardiovascular medicine · 2026
    Article
11. The Adipokine Hypothesis of Heart Failure With a Preserved Ejection Fraction: A Novel Framework to Explain Pathogenesis and Guide Treatment.Journal of the American College of Cardiology · 2025
    Review
12. Role of epicardial adipose tissue in heart failure with preserved ejection fraction: An emerging molecular mechanism and therapeutic potential.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Review
13. Early detection of left atrial dysfunction in young hypertensive patients with a normal left atrial size: a comprehensive analysis using four-dimensional auto left atrial quantification echocardiography.BMC cardiovascular disorders · 2025
    Article
14. Increased epicardial adipose tissue is associated with left atrial mechanical dysfunction in patients with heart failure with mildly reduced and preserved ejection fraction.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
15. Role of metabolic dysfunction-associated fatty liver disease in atrial fibrillation and heart failure: molecular and clinical aspects.Frontiers in cardiovascular medicine · 2025
    Review
16. Exploring the role of epicardial adipose-tissue-derived extracellular vesicles in cardiovascular diseases.iScience · 2024
    Review
17. Cellular Senescence as a Targetable Risk Factor for Cardiovascular Diseases: Therapeutic Implications:JACC. Basic to translational science · 2024
    Review
18. Improved identification of left atrial enlargement in patients with obesity.The international journal of cardiovascular imaging · 2024
    Article
19. Obesity and the risk of cardiometabolic diseases.Nature reviews. Cardiology · 2023
    Review
20. Atrial Fibrillation and Diabetes Mellitus: Dangerous Liaisons or Innocent Bystanders?Journal of clinical medicine · 2023
    Review

Corrections and comments

• Comment on
  Epicardial fat in heart failure patients with mid-range and preserved ejection fraction.2018

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as