ArticleWorld journal of urology2019
Impaired sleep is associated with low testosterone in US adult males: results from the National Health and Nutrition Examination Survey.
Article in World journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 46 citations in OpenAlex.
- Sleep Duration and Prostate Cancer Risk in the Southern Community Cohort Study.Cancer medicine · 2026Article
- Testosterone and Obesity in an Aging Society.Biomolecules · 2025Review
- A Conceptual Model Linking Benign Prostatic Hyperplasia Circadian Disruption, Testosterone Deficiency, and Frailty in Older Adults.The world journal of men's health · 2025Article
- Comment on: "Mitochondria as Nutritional Targets to Maintain Muscle Health and Physical Function During Ageing".Sports medicine (Auckland, N.Z.) · 2025Article
- Observational
- Bidirectional causal associations between frailty measures and sleep disturbances: a two-sample Mendelian randomization study.Nature and science of sleep · 2025Article
- Study protocol: associations between hormonal profile and physical and cognitive functions in middle-aged men-a one-year cohort follow-up study.Frontiers in public health · 2025Article
- Association between the oxidative balance score and testosterone deficiency in males: a cross-sectional study.Frontiers in nutrition · 2025Article
- Association Between Sleep Duration and Anxiety in US Adults: A Nationally Representative Cross-Sectional Study.Psychology research and behavior management · 2025Article
- Association between the atherogenic index of plasma and testosterone deficiency in American adults: a cross-sectional study from NHANES 2011-2016.Frontiers in endocrinology · 2025Article
- Effects of Testosterone in Mediating the Relationship Between Daytime Napping and Osteoporosis in European Populations: A Mendelian Randomization Study.Calcified tissue international · 2024Article
- Association of sleep duration and quality with serum testosterone concentrations among men and women: NHANES 2011-2016.Andrology · 2024Article
- Decrease in Sperm Parameters in the 21st Century: Obesity, Lifestyle, or Environmental Factors? An Updated Narrative Review.Journal of personalized medicine · 2024Review
- Does testosterone influence the association between sleep and frailty in men: results from the European Male Aging Study.BMC geriatrics · 2023Article
- Mitigation role of physical exercise participation in the relationship between blood cadmium and sleep disturbance: a cross-sectional study.BMC public health · 2023Article
- Association between the prevalence rates of circadian syndrome and testosterone deficiency in US males: data from NHANES (2011-2016).Frontiers in nutrition · 2023Article
- Sleep and Anabolic/Catabolic Hormonal Profile in Sedentary Middle-Aged Adults: The FIT-AGEING Study.International journal of molecular sciences · 2022Article
- Functional hypogonadism among patients with obesity, diabetes, and metabolic syndrome.International journal of impotence research · 2022Review
- Non-Right Handedness is Associated with More Time Awake After Sleep Onset and Higher Daytime Sleepiness Than Right Handedness: Objective (Actigraphic) and Subjective Data from a Large Community Sample.Nature and science of sleep · 2022Article
- Understanding the Associations of Prenatal Androgen Exposure on Sleep Physiology, Circadian Proteins, Anthropometric Parameters, Hormonal Factors, Quality of Life, and Sex Among Healthy Young Adults: Protocol for an International, Multicenter Study.JMIR research protocols · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTestosterone deficiency has been linked to several adverse health outcomes and recent data have suggested that abnormal sleep quality may result in lower testosterone levels. We assessed the effect of self-reported sleep patterns on serum testosterone while controlling for co-morbidities, and baseline demographics. MATERIALS AND
methodsUsing data collected from the 2011-2012 National Health and Nutrition Examination Survey (NHANES), we extracted serum total testosterone level, sleep duration, demographic, and co-morbidities for men aged 16 years and older. Univariate and multivariate linear regression was used to estimate the association of number of hours slept, co-morbidities, and demographics with serum testosterone.
resultsAmong the 9756 individuals in the NHANES dataset, 2295 (23.5%) were males 16 years and older with a median (interquartile range) age of 46 years (29-62) who also had serum testosterone levels drawn. Median serum testosterone level was 377 ng/dL (IQR: 279-492 ng/dL). Median number of hours slept was 7 h (IQR: 6-8 h). On multivariate linear regression, we found serum testosterone decreased by 0.49 ng/dL per year of age (p = 0.04), 5.85 ng/dL per hour loss of sleep (p < 0.01) and 6.18 ng/dL per unit of body mass index (BMI) increase (p < 0.01).
conclusionsAmong men aged 16-80 in the United States, we found increasing age, impaired sleep and elevated BMI is associated with low testosterone. It is important, therefore, that evaluation and treatment of reduced serum testosterone should also include improving sleep duration in combination with weight management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.