Evidence map›Paper›PMID 30225571›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019

The risk factors for depression in cancer patients undergoing chemotherapy: a systematic review.

Shuangshuang Wen, Huimin Xiao, Yanqing Yang

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
2.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 77 citations in OpenAlex.

  1. Depressive symptoms and perceived stress in patients with head and neck cancer undergoing intensity-modulated radiation therapy: A longitudinal study.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2026
    Article
  2. Mental illness and health literacy in people with cancer: the Australian National Health Survey analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Review
  4. Joint nausea and fatigue profiles during chemotherapy identify patients with a higher symptom burden.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Associations of personality profiles with stress and resilience characteristics among patients undergoing cancer chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
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  19. Cognitive appraisal and depression in cancer patients undergoing chemotherapy: mediation by perceived stress and self-efficacy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shuangshuang WenSchool of Nursing, Fujian Medical University, No 1 Xuefu North Road, University Town, Shangjie Zhen, Minhou County, Fuzhou City, 350122, Fujian Province, China.
Huimin XiaoSchool of Nursing, Fujian Medical University, No 1 Xuefu North Road, University Town, Shangjie Zhen, Minhou County, Fuzhou City, 350122, Fujian Province, China. huimin_xiao@126.com.ORCID http://orcid.org/0000-0001-5468-301X
Yanqing YangSchool of Nursing, Fujian Medical University, No 1 Xuefu North Road, University Town, Shangjie Zhen, Minhou County, Fuzhou City, 350122, Fujian Province, China.
Fujian Medical University · CN

Funding

National Natural Science Foundation of China 8140,1863
6 · The paper itself

Abstract

purposeThis systematic review aims to identify the risk factors for depression in cancer patients undergoing chemotherapy.

methodsEight electronic databases were searched from inception of the databases established until August 2017. References for the included studies were retrieved by manual searching. The quality of the eligible studies was appraised by two persons using the 11-item checklist of the Agency for Healthcare Research and Quality (AHRQ).

resultsAmong 5988 potentially relevant articles, 43 studies were eligible, with 17 studies of high quality and 25 studies of moderate quality. A total of 65 factors were extracted, including sociodemographic characteristics (n = 20), physiological condition (n = 20), disease and treatment (n = 12), and psychosocial factors (n = 13). Only social support, anxiety, perceived stress, and self-efficacy were found to be consistently associated with depression in cancer patients. There is not enough evidence to support the link between the other 61 factors and depression in cancer patients undergoing chemotherapy.

conclusionsThis review suggests that the development of depression programs should take social support, anxiety, perceived stress, and self-efficacy into account. More original studies with rigorous design are necessary to further confirm those 61 inconclusive risk factors for depression in cancer patients receiving chemotherapy.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsAnxietyDepressionHumansNeoplasmsQuality of LifeRisk FactorsSocial SupportStress, PsychologicalCancerChemotherapyDepressionRisk factors

Identifiers

PMID30225571
OpenAlexW2890996935

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.