Evidence map›Paper›PMID 30225457›Full record

ArticleMayo Clinic proceedings. Innovations, quality & outcomes2018

Bone Marrow Biopsy Operator Experience and Impact on Aspirate, Biopsy, and Ancillary Testing Quality.

Lisa M Marinelli, Hong Fang, Matthew T Howard, Curtis A Hanson, Joseph J Haack, Edward A Eick, Richard J Allen, David E Ruffridge, Colleen M Byrne, Rebecca L King

Registry-linked trialAbstract read
In one paragraph

Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05258357 (Landmark vs. Ultrasound-Assisted Bone Marrow Biopsy Procedure Study), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05258357 nacompletednot on this mapstarted 2022, after this paper: background citation

Landmark vs. Ultrasound-Assisted Bone Marrow Biopsy Procedure Study

TypeinterventionalSponsorMedical College of WisconsinRan2022 to 2026Enrolled100ConditionsBone Marrow Biopsy ProcedureArmsUltrasound-assisted bone marrow biopsy, Landmark palpation bone marrow biopsy
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lisa M MarinelliMayo Clinic School of Medicine, Mayo Clinic, Rochester, MN.
Hong FangDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
Matthew T HowardDivision of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
Curtis A HansonDivision of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
Joseph J HaackDivision of Hematology, Mayo Clinic, Rochester, MN.
Edward A EickDivision of Hematology, Mayo Clinic, Rochester, MN.
Richard J AllenDivision of Hematology, Mayo Clinic, Rochester, MN.
David E RuffridgeDivision of Hematology, Mayo Clinic, Rochester, MN.
Colleen M ByrneDivision of Hematology, Mayo Clinic, Rochester, MN.
Rebecca L KingDivision of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the relationship between bone marrow (BM) biopsy operator experience and both specimen quality and ancillary testing utilization. PATIENTS AND

methodsWe evaluated all referred and in-house (IH) BM biopsy specimens obtained over a contiguous 6-week period from April 3, 2017, to May 19, 2017. The BM specimens were assessed for the length of interpretable marrow, and aspirates were assessed for the presence of spicules. Subgroup comparisons included IH BM obtained by a trained team of nurses within our institution, patients clinically referred (CR) to our institution with outside-obtained BM specimens, and outside pathologist-referred (PR) consultation cases. Ancillary study usage was compared between the first 100 cases of each group.

resultsA total of 1191 BM specimens were analyzed, including 600 IH, 288 CR, and 303 PR cases with biopsies and/or aspirates. The average interpretable biopsy lengths of IH, CR, and PR cases were 16.0 mm, 10.0 mm, and 7.0 mm, respectively (

conclusionHaving a dedicated team of BM biopsy operators is likely one factor contributing to improved BM biopsy quality and a reduced need for ancillary testing.

Indexed as

BM, bone marrowCR, clinically referredIHC, immunohistochemicalIH, in-housePR, pathologist referredWHO, World Health Organization

Identifiers

PMID30225457
PMCPMC6132213

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