Evidence map›Paper›PMID 30225450›Full record

ArticleMayo Clinic proceedings. Innovations, quality & outcomes2018

Flow-Mediated Slowing as a Methodological Alternative to the Conventional Echo-Tracking Flow-Mediated Dilation Technique for the Evaluation of Endothelial Function: A Preliminary Report.

Telmo Pereira, Armindo Almeida, Jorge Conde

Open access · goldAbstract read
In one paragraph

Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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  8. From Taking First Steps to Hitting Our Stride.Mayo Clinic proceedings. Innovations, quality & outcomes · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Telmo PereiraPolytechnic Institute of Coimbra, Coimbra Health School, Coimbra, Portugal.
Armindo AlmeidaPolytechnic Institute of Coimbra, Coimbra Health School, Coimbra, Portugal.
Jorge CondePolytechnic Institute of Coimbra, Coimbra Health School, Coimbra, Portugal.
Polytechnic Institute of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Moens-Korteweg equation predicts changes in pulse wave velocity (PWV) after changes in arterial radius; therefore, an increase in arterial radius, as seen in a reactive hyperemia (RH) condition, should slow PWV over a given arterial segment. If this assumption is true, then the deceleration of PWV over the brachial artery (flow-mediated slowing [FMS]) should be an equivalent signal of endothelial function during a conventional RH flow-mediated dilation (FMD) procedure. Our aim was to compare FMS with FMD after RH in healthy individuals as part of a study that seeks to evaluate the clinical usefulness of FMS as a noninvasive approach to characterize endothelial function. This cross-sectional study included 25 healthy participants (18 women [72%]) with a mean ± SD age of 21.12±0.73 years. The FMD and FMS were simultaneously measured. A significant correlation was observed between both measures of FMS (absolute difference and percentage variation) and echo FMD:

Indexed as

ED, endothelial dysfunctionEF, endothelial functionFMD, flow-mediated dilationFMS, flow-mediated slowingPWV, pulse wave velocityRH, reactive hyperemia

Identifiers

PMID30225450
PMCPMC6124332
OpenAlexW2791608309

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.