ArticleeNeuro
Sodium Channel-Dependent and -Independent Mechanisms Underlying Axonal Afterdepolarization at Mouse Hippocampal Mossy Fibers.
Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- KThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Ectopic burst induced by blockade of axonal potassium channels on the mouse hippocampal mossy fiber.Frontiers in cellular neuroscience · 2024Article
- Modeling analysis of subthreshold voltage signaling along hippocampal mossy fiber axons.Frontiers in cellular neuroscience · 2022Article
- The Slow Depolarization Following Individual Spikes in Thin, Unmyelinated Axons in Mammalian Cortex.Frontiers in cellular neuroscience · 2019Article
- Excitability Tuning of Axons by Afterdepolarization.Frontiers in cellular neuroscience · 2019Review
- Modeling Analysis of Axonal After Potential at Hippocampal Mossy Fibers.Frontiers in cellular neuroscience · 2019Article
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
Action potentials propagating along axons are often followed by prolonged afterdepolarization (ADP) lasting for several tens of milliseconds. Axonal ADP is thought to be an important factor in modulating the fidelity of spike propagation during repetitive firings. However, the mechanism as well as the functional significance of axonal ADP remain unclear, partly due to inaccessibility to small structures of axon for direct electrophysiological recordings. Here, we examined the ionic and electrical mechanisms underlying axonal ADP using whole-bouton recording from mossy fiber terminals in mice hippocampal slices. ADP following axonal action potentials was strongly enhanced by focal application of veratridine, an inhibitor of Na
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