Evidence map›Paper›PMID 30225233›Full record

ReviewInternational journal of ophthalmology2018

Research progress on the role of connective tissue growth factor in fibrosis of diabetic retinopathy.

Teng Ma, Li-Jie Dong, Xue-Li Du, Rui Niu, Bo-Jie Hu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Connective Tissue Growth Factor: Regulation, Diseases, and Drug Discovery.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Teng MaTianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, Ophthalmology College of Tianjin Medical University, Tianjin 300384, China.
Li-Jie DongTianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, Ophthalmology College of Tianjin Medical University, Tianjin 300384, China.
Xue-Li DuTianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, Ophthalmology College of Tianjin Medical University, Tianjin 300384, China.
Rui NiuTianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, Ophthalmology College of Tianjin Medical University, Tianjin 300384, China.
Bo-Jie HuTianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, Ophthalmology College of Tianjin Medical University, Tianjin 300384, China.
Tianjin Medical University Eye Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic retinopathy (DR) is one of the most important types of diabetic microangiopathy, which is a specific change of fundus lesions and is one of the most serious complications of diabetes. When DR develops to proliferative DR, the main factors of decreasing vision, and even blindness, include retinal detachment and vitreous hemorrhage caused by contraction of blood vessels by fiber membrane. Recent studies reported that the formation of fiber vascular membrane is closely related to retinal fibrosis. The connective tissue growth factor (CTGF) is a cytokine that is closely related to DR fibrosis. However, its mechanism is poorly understood. This paper summarizes the recent studies about CTGF on DR fibrosis for a comprehensive understanding of the role and mechanism of CTGF in PDR.

Indexed as

connective tissue growth factorfibrosisproliferative diabetic retinopathyvascular endothelial growth factor

Identifiers

PMID30225233
PMCPMC6133890
OpenAlexW2897978061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.