Evidence map›Paper›PMID 30225228›Full record

ArticleInternational journal of ophthalmology2018

Multimodal imaging in acute retinal ischemia: spectral domain OCT, OCT-angiography and fundus autofluorescence.

Nikolaus Feucht, Daniel Zapp, Lukas Reznicek, Chris P Lohmann, Mathias Maier, Christian S Mayer

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Acute macular neuroretinopathy: is the name still appropriate?Medical hypothesis, discovery & innovation ophthalmology journal · 2026
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  10. Multimodal Imaging of Acute Central Retinal Artery Occlusion.Medical hypothesis, discovery & innovation ophthalmology journal · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nikolaus FeuchtDepartment of Ophthalmology, Technical University of Munich, Munich 81675, Germany.
Daniel ZappDepartment of Ophthalmology, Technical University of Munich, Munich 81675, Germany.
Lukas ReznicekDepartment of Ophthalmology, Technical University of Munich, Munich 81675, Germany.
Chris P LohmannDepartment of Ophthalmology, Technical University of Munich, Munich 81675, Germany.
Mathias MaierDepartment of Ophthalmology, Technical University of Munich, Munich 81675, Germany.
Christian S MayerDepartment of Ophthalmology, Technical University of Munich, Munich 81675, Germany.
Technical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo describe retinal findings of various imaging modalities in acute retinal ischemia.

methodsFluorescein angiography (FA), spectral domain optical coherence tomography (SD-OCT), OCT-angiography (OCT-A) and fundus autofluorescence (FAF) images of 13 patients (mean age 64y, range 28-86y) with acute retinal ischemia were evaluated. Six suffered from branch arterial occlusion, 2 had a central retinal artery occlusion, 2 had a combined arteriovenous occlusions, 1 patient had a retrobulbar arterial compression by an orbital haemangioma and 2 patients showed an ocular ischemic syndrome.

resultsAll patients showed increased reflectivity and thickening of the ischemic retinal tissue. In 10 out of 13 patients SD-OCT revealed an additional highly reflective band located within or above the outer plexiform layer. Morphological characteristics were a decreasing intensity with distance from the fovea, partially segmental occurrence and manifestation limited in time. OCT-A showed a loss of flow signal in the superficial and deep capillary plexus at the affected areas. Reduced flow signal was detected underneath the regions with retinal edema. FAF showed areas of altered signal intensity at the posterior pole. The regions of decreased FAF signal corresponded to peri-venous regions.

conclusionMultimodal imaging modalities in retinal ischemia yield characteristic findings and valuable diagnostic information. Conventional OCT identifies hyperreflectivity and thickening and a mid-retinal hyperreflective band is frequently observed. OCT-A examination reveals demarcation of the ischemic retinal area on the vascular level. FAF shows decreased fluorescence signal in areas of retinal edema often corresponding to peri-venous regions.

Indexed as

acute retinal ischemiamultimodal retinal imagingoptical coherence tomographyoptical coherence tomography-angiographyretinal blood flowretinal morphology

Identifiers

PMID30225228
PMCPMC6133900
OpenAlexW2897406836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.