Evidence map›Paper›PMID 30224937›Full record

ArticleDisease markers2018

A Novel Technique of Spectral Discrimination of Variants of Sickle Cell Anemia.

Vadivel Masilamani, Sandanasamy Devanesan, Fatma AlQathani, Mashael AlShebly, Hebatullah Hassan Daban, Duran Canatan, Karim Farhat, Mansour Jabry, Mohamad S AlSalhi

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Vadivel MasilamaniDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh, Saudi Arabia.ORCID 0000-0001-8588-6661
Sandanasamy DevanesanDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh, Saudi Arabia.
Fatma AlQathaniHematology Unit, Department of Pathology, College of Medicine, King Saud University and King Saud University Medical City, Riyadh, Saudi Arabia.
Mashael AlSheblyDepartment of Obstetrics and Gynecology, College of Medicine, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.ORCID 0000-0001-5459-8130
Hebatullah Hassan DabanDepartment of Physics and Astronomy, College of Science, King Saud University (Ladies Section), Riyadh, Saudi Arabia.
Duran CanatanHemoglobinopathy Diagnosis Center of Mediterranean Blood Diseases Foundation, Antalya, Turkey.ORCID 0000-0003-3183-2208
Karim FarhatCancer Research Chair, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-1871-2818
Mansour JabryHematology Unit, Department of Pathology, College of Medicine, King Saud University and King Saud University Medical City, Riyadh, Saudi Arabia.ORCID 0000-0001-6198-4574
Mohamad S AlSalhiDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh, Saudi Arabia.ORCID 0000-0002-8249-4256
King Saud University · SAKing Saud Medical City · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sickle cell anemia (SCA) is an inherited blood disorder with worldwide incidence of 15%; out of this, it is found in up to 20% in countries like Kingdom of Saudi Arabia and Bahrain. The standard conventional method of detection is complete blood count (CBC) followed by hemoglobin electrophoresis or high-performance liquid chromatography (HPLC) or both. In this context, spectral detection of variants of sickle cell anemia (SCA) is an innovative technique, which when made accurate and reliable could be an effective alternative, since the instrumentation is compact (5 kg) and hence portable. This makes mass screening even in remote villages possible. In this paper, we give the essential aspects of fluorescent spectral features of sickle cell trait (SCT), sickle cell disease (SCD), beta (

Indexed as

AdolescentAdultAnemia, Sickle Cellbeta-ThalassemiaCase-Control StudiesFemaleHumansMaleSickle Cell TraitSpectrometry, FluorescenceYoung Adult

Identifiers

PMID30224937
PMCPMC6129790
OpenAlexW2889358547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.