Evidence map›Paper›PMID 30224923›Full record

ArticleStem cells international2018

Potential Effect of Exosomes Derived from Cancer Stem Cells and MSCs on Progression of DEN-Induced HCC in Rats.

Faisal A Alzahrani, Mohammed A El-Magd, Ahmed Abdelfattah-Hassan, Ayman A Saleh, Islam M Saadeldin, Eman S El-Shetry, Abdelnaser A Badawy, Saleh Alkarim

Open access · goldAbstract read
In one paragraph

Article in Stem cells international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 1 synthesis or guideline pooled it, 156 citations in OpenAlex.

  1. Pooled it
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  8. Crosstalk between MSC-extracellular vesicles andFrontiers in pharmacology · 2025
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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Faisal A AlzahraniDepartment of Biological Sciences, Rabigh College of Science and Arts, King Abdulaziz University (Jeddah), Rabigh Branch, Rabigh 21911, Saudi Arabia.
Mohammed A El-MagdDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Kafrelsheikh University, Postal Box, Kafr El Sheikh 33516, Egypt.ORCID 0000-0002-3314-9202
Ahmed Abdelfattah-HassanDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Zagazig University, Postal Box, Zagazig 44519, Egypt.ORCID 0000-0003-3478-1098
Ayman A SalehDepartment of Animal Wealth Development, Genetics and Genetic Engineering, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
Islam M SaadeldinDepartment of Animal Production, College of Food and Agricultural Science, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-7633-730X
Eman S El-ShetryDepartment of Human Anatomy and Embryology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Abdelnaser A BadawyDepartment of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Saleh AlkarimDepartment of Biology, College of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
Zagazig University · EGKing Abdulaziz University · SAKafrelsheikh University · EGMansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cross talk, mediated by exosomes, between normal stem cells and cancer stem cells (CSCs) in the tumor microenvironment has been given less attention so far. In addition, no publications are available in the literature that address the

Identifiers

PMID30224923
PMCPMC6129855
OpenAlexW2889434118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.