Evidence map›Paper›PMID 30224828›Full record

ArticleScientific reports2018

Personality Profiles Are Associated with Functional Brain Networks Related to Cognition and Emotion.

Peter Mulders, Alberto Llera, Indira Tendolkar, Philip van Eijndhoven, Christian Beckmann

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  5. Autism Is Associated With Interindividual Variations of Gray and White Matter Morphology.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023
    Article
  6. Article
  7. [Cross subject personality assessment based on electroencephalogram functional connectivity and domain adaptation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2022
    Article
  8. Lesions in different prefrontal sectors are associated with different types of acquired personality disturbances.Cortex; a journal devoted to the study of the nervous system and behavior · 2022
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peter MuldersDepartment of Psychiatry, Radboud University Medical Center, 6500 HB, Nijmegen, The Netherlands. petercr.mulders@radboudumc.nl.
Alberto LleraDonders Institute for Brain, Cognition and Behavior, Centre for Cognitive Neuroimaging, 6500 GL, Nijmegen, The Netherlands.
Indira TendolkarDepartment of Psychiatry, Radboud University Medical Center, 6500 HB, Nijmegen, The Netherlands.
Philip van EijndhovenDepartment of Psychiatry, Radboud University Medical Center, 6500 HB, Nijmegen, The Netherlands.
Christian BeckmannDonders Institute for Brain, Cognition and Behavior, Centre for Cognitive Neuroimaging, 6500 GL, Nijmegen, The Netherlands.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
Nederlandse Organisatie voor Wetenschappelijk Onderzoek (Netherlands Organisation for Scientific Research) NWO-Vidi 864-12NIMH NIH HHS U54 MH091657Wellcome Trust
6 · The paper itself

Abstract

Personality factors as defined by the "five-factor model" are some of the most investigated characteristics that underlie various types of complex behavior. These are, however, often investigated as isolated traits that are conceptually independent, yet empirically are typically strongly related to each other. We apply Independent Component Analysis to these personality factors as measured by the NEO-FFI in 471 healthy subjects from the Human Connectome Project to investigate independent personality profiles that incorporate all five original factors. Subsequently we examine how these profiles are related to patterns of resting-state brain activity in specific networks-of-interest related to cognition and emotion. We find that a personality profile of contrasting openness and agreeableness is associated with engagement of a subcortical-medial prefrontal network and the dorsolateral prefrontal cortex. Likewise, a profile of contrasting extraversion and conscientiousness is associated with activity in the precuneus. This study shows a novel approach to investigating personality and how it is related to patterns of activity in the resting brain.

Indexed as

CognitionConnectomeEmotionsPersonalityAdultBrainBrain MappingFemaleHumansMagnetic Resonance ImagingMalePersonality DisordersReproducibility of ResultsRestYoung Adult

Identifiers

PMID30224828
PMCPMC6141550

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.