SynthesisScientific reports2018
Impact of timing of surgery in elderly hip fracture patients: a systematic review and meta-analysis.
Synthesis in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 231 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
231 citing papers in PubMed, 9 syntheses or guidelines pooled it, 425 citations in OpenAlex.
- Association between timing of surgery and postoperative outcomes in older adults with distal femur fractures: a systematic review and meta-analysis.Archives of orthopaedic and trauma surgery · 2026Pooled it
- Risk factors for hospital-acquired pneumonia in hip fracture patients: A systematic review and meta-analysis.Medicine · 2024Pooled it
- Risk factors for hospital-acquired pneumonia in hip fracture patients: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2024Pooled it
- The impact of electronic pathways and digital systems on neck of femur fracture outcomes globally: a systematic review.Annals of the Royal College of Surgeons of England · 2023Pooled it
- Perioperative interventions to improve early mobilisation and physical function after hip fracture: a systematic review and meta-analysis.Age and ageing · 2023Pooled it
- Correlation between C-reactive protein and postoperative mortality in patients undergoing hip fracture surgery: a meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- What are Risk Factors of Postoperative Pneumonia in Geriatric Individuals after Hip Fracture Surgery: A Systematic Review and Meta-Analysis.Orthopaedic surgery · 2023Pooled it
- Synthesis of the evidence on the impact of pre-operative direct oral anticoagulants on patient health outcomes after hip fracture surgery: rapid systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Pooled it
- Effects of Orthogeriatric Care Models on Outcomes of Hip Fracture Patients: A Systematic Review and Meta-Analysis.Calcified tissue international · 2022Pooled it
- Endoprosthetic reconstruction versus osteosynthesis for metastatic disease of the proximal femur: a population-based cohort study.Journal of bone oncology · 2026Article
- Hip Fracture Management in Older Adults in Resource-Constrained Settings: Determinants, Care Pathways, and Outcomes-A Systematic Review and Meta-Analysis.Health science reports · 2026Review
- Health economic evaluation of hip fracture care pathways in The Gambia.BMJ global health · 2026Article
- Waiting time and mortality after hip fracture: findings from a large single-center cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Establishing Independent Predictors of Early Geriatric Hip Fracture Surgery.Hip & pelvis · 2026Article
- Preoperative stay under 48 h after admission for proximal femur fractures is linked to fewer complications and better outcomes.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Timing of surgery in patients with hip fracture: a systematic review with meta-analysis and trial sequential analysis (2017-2024).EFORT open reviews · 2026Article
- Age- and sex-specific incidence rates and future projections for hip fractures in The Gambia, West Africa, and comparison across four countries in Africa.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026Article
- Postoperative analgesic outcomes of fascia iliaca compartment block versus pericapsular nerve group block in hip fracture surgery: a retrospective observational study.BMC anesthesiology · 2026Observational
- The 24-Hour Window: How Time to Admission Reshapes the Impact of Surgical Delay on Mortality in Elderly Hip Fracture.Journal of clinical medicine · 2026Article
- When the Heart and Hip Collide: The Interplay Between Atrial Fibrillation and Neck of Femur Fractures.Journal of cardiovascular development and disease · 2026Review
171 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to assess the impact of timing of surgery in elderly patients with acute hip fracture on morbidity and mortality. We systematically searched MEDLINE, the Cochrane Library, Embase, PubMed, and trial registries from 01/1997 to 05/2017, as well as reference lists of relevant reviews, archives of orthopaedic conferences, and contacted experts. Eligible studies had to be randomised controlled trials (RCTs) or prospective cohort studies, including patients 60 years or older with acute hip fracture. Two authors independently assessed study eligibility, abstracted data, and critically appraised study quality. We conducted meta-analyses using the generic inverse variance model. We included 28 prospective observational studies reporting data of 31,242 patients. Patients operated on within 48 hours had a 20% lower risk of dying within 12 months (risk ratio (RR) 0.80, 95% confidence interval (CI) 0.66-0.97). No statistical significant different mortality risk was observed when comparing patients operated on within or after 24 hours (RR 0.82, 95% CI 0.67-1.01). Adjusted data demonstrated fewer complications (8% vs. 17%) in patients who had early surgery, and increasing risk for pressure ulcers with increased time of delay in another study. Early hip surgery within 48 hours was associated with lower mortality risk and fewer perioperative complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.