ArticleScientific reports2018
Spatio-temporal characteristics of population responses evoked by microstimulation in the barrel cortex.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Article
- Neural population dynamics of direct electrical stimulation of neocortex.Cell reports · 2026Article
- Biased inter-columnar communication and short-term plasticity in mouse barrel cortex.bioRxiv : the preprint server for biology · 2026Article
- Neural population dynamics of direct electrical stimulation of neocortex.bioRxiv : the preprint server for biology · 2025Article
- Microstimulation-based path tracking control of pigeon robots through parameter adaptive strategy.Heliyon · 2024Article
- Spatio-temporal activation patterns of neuronal population evoked by optostimulation and the comparison to electrical microstimulation.Scientific reports · 2023Article
- Characterizing the short-latency evoked response to intracortical microstimulation across a multi-electrode array.Journal of neural engineering · 2022Article
- Visualizing Oscillations in Brain Slices With Genetically Encoded Voltage Indicators.Frontiers in neuroanatomy · 2021Article
- Article
- Widespread activation of awake mouse cortex by electrical stimulation.International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering · 2019Article
- Neural mechanisms of the temporal response of cortical neurons to intracortical microstimulation.Brain stimulationArticle
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2 authors.
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Abstract
Intra-cortical microstimulation (ICMS) is a widely used technique to artificially stimulate cortical tissue. This method revealed functional maps and provided causal links between neuronal activity and cognitive, sensory or motor functions. The effects of ICMS on neural activity depend on stimulation parameters. Past studies investigated the effects of stimulation frequency mainly at the behavioral or motor level. Therefore the direct effect of frequency stimulation on the evoked spatio-temporal patterns of cortical activity is largely unknown. To study this question we used voltage-sensitive dye imaging to measure the population response in the barrel cortex of anesthetized rats evoked by high frequency stimulation (HFS), a lower frequency stimulation (LFS) of the same duration or a single pulse stimulation. We found that single pulse and short trains of ICMS induced cortical activity extending over few mm. HFS evoked a lower population response during the sustained response and showed a smaller activation across time and space compared with LFS. Finally the evoked population response started near the electrode site and spread horizontally at a propagation velocity in accordance with horizontal connections. In summary, HFS was less effective in cortical activation compared to LFS although HFS had 5 fold more energy than LFS.
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