ArticleScientific reports2018
Low fasting plasma glucose level as a predictor of new-onset diabetes mellitus on a large cohort from a Japanese general population.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
- The 6-Month Efficacy of an Intensive Lifestyle Modification Program on Type 2 Diabetes Risk Among Rural Women with Prior Gestational Diabetes Mellitus: a Cluster Randomized Controlled Trial.Prevention science : the official journal of the Society for Prevention Research · 2022Trial
- Eating Dinner Early Improves 24-h Blood Glucose Levels and Boosts Lipid Metabolism after Breakfast the Next Day: A Randomized Cross-Over Trial.Nutrients · 2021Trial
- A comparison of blood pressure reference values and the prevalence of high blood pressure in Indian adolescents aged 10-16 years using American and Indian reference standards.Clinical hypertension · 2026Article
- Preconception hypoglycemia and adverse pregnancy outcomes in Chinese women aged 20-49 years: A retrospective cohort study in China.PLoS medicine · 2025Article
- J-shape relationship between normal fasting plasma glucose and risk of type 2 diabetes in the general population: results from two cohort studies.Journal of translational medicine · 2023Article
- A Prediction Model of the Incidence of Type 2 Diabetes in Individuals with Abdominal Obesity: Insights from the General Population.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Fasting glucose level and all-cause or cause-specific mortality in Korean adults: a nationwide cohort study.The Korean journal of internal medicine · 2021Article
- Derivation and Validation of a Prediction Model for Predicting the 5-Year Incidence of Type 2 Diabetes in Non-Obese Adults: A Population-Based Cohort Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Association of MC4R (rs17782313) with diabetes and cardiovascular disease in Korean men and women.BMC medical genetics · 2020Article
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Authors and funding
16 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although fasting plasma glucose levels <70 mg/dL are associated with a high incidence of cardiovascular disease (CVD), whether there is any risk of new-onset diabetes mellitus owing to fasting plasma glucose at this range has not been clarified. We measured the odds ratio (OR) of new-onset diabetes mellitus relative to fasting plasma glucose levels at various ranges in a nation-wide Japanese population with and without CVD history. Of 186,749 participants without diabetes in 2008, 171,408 had no history of CVD, while 15,341 did. Participants were classified into 8 categories according to their fasting plasma glucose levels. Unadjusted and multivariable-adjusted logistic regression models were used to measure the OR of new-onset diabetes mellitus in the 3-year follow up. In all participants, multivariable-adjusted OR increased when fasting plasma glucose levels were <70 mg/dL or 90-125 mg/dL. Participants without CVD showed increased OR when glucose levels were <70 mg/dL or 90-125 mg/dL. Participants with a history of CVD showed increased OR with glucose levels of 95-125 mg/dL. The risk of new-onset diabetes mellitus is higher when fasting glucose levels are <70 mg/dL, indicating that the paradox of fasting glucose seeks a new risk stratification for new-onset diabetes mellitus.
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