Evidence map›Paper›PMID 30224527›Full record

ArticleAntimicrobial agents and chemotherapy2018

Synergistic Antimicrobial Activity of Colistin in Combination with Rifampin and Azithromycin against Escherichia coli Producing MCR-1.

Yanqin Li, Xiaohuan Lin, Xuan Yao, Yan Huang, Wenguang Liu, Tao Ma, Binghu Fang

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Upregulation of outer membrane porin geneMicrobiology spectrum · 2024
    Article
  3. Mechanistic insight into the synergistic antimicrobial potential ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Global epidemiology, genetic environment, risk factors and therapeutic prospects ofFrontiers in cellular and infection microbiology · 2022
    Review
  10. Article
  11. Colistin resistance inMicrobiology (Reading, England) · 2021
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Recent progress on elucidating the molecular mechanism of plasmid-mediated colistin resistance and drug design.International microbiology : the official journal of the Spanish Society for Microbiology · 2020
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yanqin LiDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Xiaohuan LinDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Xuan YaoDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Yan HuangDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Wenguang LiuDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Tao MaDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Binghu FangDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China fangbh@scau.edu.cn.
South China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lack of available antibiotics is a global public health problem due to the emergence of antimicrobial resistance. Effective therapeutic regimens are urgently needed against

Indexed as

AnimalsAnti-Bacterial AgentsAzithromycinColistinColony Count, MicrobialDrug CombinationsDrug Resistance, Multiple, BacterialDrug SynergismEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsGene ExpressionMaleMiceMice, Inbred ICRMicrobial Sensitivity TestsAnti-Bacterial AgentsAzithromycinColistinDrug CombinationsEscherichia coli ProteinsMCR-1 protein, E coliRifampinazithromycincolistinEscherichia colimcr-1rifampin

Identifiers

PMID30224527
PMCPMC6256761
OpenAlexW2889954111

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.