Evidence map›Paper›PMID 30224518›Full record

ArticleMolecular and cellular biology2018

Deficiency of the Endocytic Protein Hip1 Leads to Decreased

Ranjula Wijayatunge, Sam R Holmstrom, Samantha B Foley, Victoria E Mgbemena, Varsha Bhargava, Gerardo Lopez Perez, Kelly McCrum, Theodora S Ross

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and cellular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ranjula WijayatungeDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Sam R HolmstromDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Samantha B FoleyDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Victoria E MgbemenaDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Varsha BhargavaDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Gerardo Lopez PerezDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Kelly McCrumDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Theodora S RossDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA theo.ross@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · US

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Sandi Leigh Pruitt · 2010 to 2026
$53.7M
Huntington Interacting Protein-1(HIP1) and the Promotion of NeoplasiaR01CA098730 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI ROSS, THEODORA S · 2003 to 2012
$2.6M
MECHANISM OF TRANSFORMATION BY HIP1/PDGFBRR01CA082363 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ROSS, THEODORA S · 2000 to 2004
$1.3M
NCI NIH HHS P30 CA142543NCI NIH HHS R01 CA082363NCI NIH HHS R01 CA098730
6 · The paper itself

Abstract

Deficiency of huntingtin-interacting protein 1 (Hip1) results in degenerative phenotypes. Here we generated a

Indexed as

AnimalsDNA-Binding ProteinsDNA, ComplementaryDown-RegulationEndocytosisGene ExpressionHumansIntronsMiceMice, Inbred C57BLMice, KnockoutPhenotypePhosphoric Diester HydrolasesPhosphorylcholineDNA-Binding ProteinsDNA, Complementaryglycerophosphodiester phosphodiesteraseHIP1 protein, humanHip1 protein, mousePhosphoric Diester HydrolasesPhosphorylcholineCre recombinaseendocytosisGDE7GDPD3HIP1kypholordosisphosphocholine

Identifiers

PMID30224518
PMCPMC6234285
OpenAlexW2951912841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.