Evidence map›Paper›PMID 30224496›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

The PqsE and RhlR proteins are an autoinducer synthase-receptor pair that control virulence and biofilm development in

Sampriti Mukherjee, Dina A Moustafa, Vasiliki Stergioula, Chari D Smith, Joanna B Goldberg, Bonnie L Bassler

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Raphani Semen Extract Targets theFood science & nutrition · 2026
    Article
  6. Review
  7. New inhibitors of themSphere · 2026
    Article
  8. Article
  9. Article
  10. Targeting biofilm and virulence inMicrobiology spectrum · 2026
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Dickeya zeae WH1 as sensor for cost-effective detection of pyocyanin produced by Pseudomonas aeruginosa.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. PqsE adapts the activity of theJournal of bacteriology · 2025
    Article
  20. MvfR ShapesCells · 2025
    Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Sampriti MukherjeeDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544.
Dina A MoustafaDepartment of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, Inc., Atlanta, GA 30322.
Vasiliki StergioulaDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544.
Chari D SmithDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544.
Joanna B GoldbergDepartment of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, Inc., Atlanta, GA 30322.
Bonnie L BasslerDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544; bbassler@princeton.edu.
Princeton University · USChildren's Healthcare of Atlanta · USEmory University · USHoward Hughes Medical Institute · US

Funding

Intra-and Inter-Species Communication in BacteriaR01GM065859 · NIGMS · PRINCETON UNIVERSITY · PI BASSLER, BONNIE L · 2002 to 2015
$4.2M
Intra- and Inter- Species Communication in BacteriaR37GM065859 · NIGMS · PRINCETON UNIVERSITY · PI BASSLER, BONNIE L · 2016 to 2025
$3.4M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM065859NIGMS NIH HHS R37 GM065859
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ProteinsBiofilmsPseudomonas aeruginosaQuorum SensingThiolester HydrolasesBacterial ProteinsRhlR protein, Pseudomonas aeruginosaThiolester HydrolasesantimicrobialbiofilmsPseudomonas aeruginosaquorum sensingvirulence

Identifiers

PMID30224496
PMCPMC6176596
OpenAlexW2889793193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.