ArticleProceedings of the National Academy of Sciences of the United States of America2018
Converging evidence for functional and structural segregation within the left ventral occipitotemporal cortex in reading.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 4 of them syntheses that pooled it.
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Who cites it
98 citing papers in PubMed, 4 syntheses or guidelines pooled it, 191 citations in OpenAlex.
- Culture Shapes the Neural Functional Alteration and Its Development in Children With Dyslexia: A Cross-Linguistic Meta-Analysis.Developmental science · 2026Pooled it
- What do we know about the Vertical Occipital Fasciculus? A systematic review.Brain structure & function · 2026Pooled it
- Brain-wide decoding of numbers and letters: Converging evidence from multivariate fMRI analysis and probabilistic meta-analysis.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Pooled it
- Is human face recognition lateralized to the right hemisphere due to neural competition with left-lateralized visual word recognition? A critical review.Brain structure & function · 2022Pooled it
- Reading instruction causes changes in category-selective visual cortex.Brain research bulletin · 2024Trial
- Simultaneous Cortical Responses to Multiple Written Words.Journal of cognitive neuroscience · 2026Article
- Anatomy of the Visual Word Form Area in Dyslexia.bioRxiv : the preprint server for biology · 2026Article
- Context-dependent reconfiguration of functional connectivity in posterior (VWFA-1) and anterior (VWFA-2) visual word form area under attentional and linguistic demands.Behavioral and brain functions : BBF · 2026Article
- The reading brain - Transforming vision into language.Progress in neurobiology · 2026Review
- Simultaneous cortical responses to multiple written words.bioRxiv : the preprint server for biology · 2026Article
- Similarities (and Differences) in the Learning Patterns of Single-Word Reading of an Alphabetic Orthography in Monolingual and Bilingual Primary School Children: A Cross-Sectional Study.Brain sciences · 2026Article
- The Emergence of Topography and Hemispheric Lateralization in High-Level Vision.Quarterly journal of experimental psychology (2006) · 2026Review
- A Matter of Font: Visual Word Form Area Responses to Brand Names Are More Sensitive to Font Than to Letter Case Changes.Neurobiology of language (Cambridge, Mass.) · 2026Article
- The balance between stability and plasticity of the visual word form area in dyslexia.Nature communications · 2025Article
- Structural and pragmatic language skills in school-age children relate to resting state functional connectivity.Brain imaging and behavior · 2025Article
- Neural Distinction between Visual Word and Object Recognition: An fMRI Study Using Pictographs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Phonological Representations of Auditory and Visual Speech in the Occipito-temporal Cortex and Beyond.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Similar Computational Hierarchies for Reading and Speech in the Occipital Cortex of Sighed and Blind: Converging Evidence from fMRI and Chronometric TMS.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Growing together: Dynamic connectivity between developmentally sensitive regions serving verbal working memory in children and adolescents.The Journal of physiology · 2025Article
- White matter connections of human ventral temporal cortex are organized by cytoarchitecture, eccentricity and category-selectivity from birth.Nature human behaviour · 2025Article
38 more citing papers are in PubMed but not listed here.
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3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ventral occipitotemporal cortex (vOTC) is crucial for recognizing visual patterns, and previous evidence suggests that there may be different subregions within the vOTC involved in the rapid identification of word forms. Here, we characterize vOTC reading circuitry using a multimodal approach combining functional, structural, and quantitative MRI and behavioral data. Two main word-responsive vOTC areas emerged: a posterior area involved in visual feature extraction, structurally connected to the intraparietal sulcus via the vertical occipital fasciculus; and an anterior area involved in integrating information with other regions of the language network, structurally connected to the angular gyrus via the posterior arcuate fasciculus. Furthermore, functional activation in these vOTC regions predicted reading behavior outside of the scanner. Differences in the microarchitectonic properties of gray-matter cells in these segregated areas were also observed, in line with earlier cytoarchitectonic evidence. These findings advance our understanding of the vOTC circuitry by linking functional responses to anatomical structure, revealing the pathways of distinct reading-related processes.
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