Evidence map›Paper›PMID 30224436›Full record

ArticleJournal of bacteriology2018

Floxed-Cassette Allelic Exchange Mutagenesis Enables Markerless Gene Deletion in Chlamydia trachomatis and Can Reverse Cassette-Induced Polar Effects.

G Keb, R Hayman, K A Fields

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 43 citations in OpenAlex.

  1. ThemBio · 2026
    Article
  2. Review
  3. Article
  4. ThebioRxiv : the preprint server for biology · 2025
    Article
  5. mSphere · 2025
    Article
  6. Journal of bacteriology · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Advances in genetic manipulation ofFrontiers in immunology · 2023
    Review
  16. Frontiers in cellular and infection microbiology · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

G KebDepartment of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
R HaymanDepartment of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
K A FieldsDepartment of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA Ken.fields@uky.edu.
University of Kentucky · US

Funding

Type III exported effectors of Chlamydia trachomatisR01AI065530 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI FIELDS, KENNETH A · 2005 to 2021
$5.7M
Mutagenesis in Chlamydia trachomatis via allelic exchangeR21AI124649 · NIAID · UNIVERSITY OF KENTUCKY · PI FIELDS, KENNETH A · 2016 to 2017
$409k
NIAID NIH HHS R01 AI065530NIAID NIH HHS R21 AI124649
6 · The paper itself

Abstract

As obligate intracellular bacteria,

Indexed as

Gene DeletionBacterial ProteinsChlamydia trachomatisDrug Resistance, BacterialGene Expression Regulation, BacterialGreen Fluorescent ProteinsHeLa CellsHumansIntegrasesMutagenesis, InsertionalBacterial ProteinsCre recombinaseGreen Fluorescent ProteinsIntegrasesChlamydiaFRAEMmutagenesisTmeAtype III secretion

Identifiers

PMID30224436
PMCPMC6256029
OpenAlexW2891727496

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.