ArticleBMJ open2018
Haemoglobin A1c and hearing impairment: longitudinal analysis using a large occupational health check-up data of Japan.
Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Hearing Health Monitoring in Adults Living with Diabetes: A Scoping Review to Inform Integrated Care Pathways.Audiology research · 2026Review
- Article
- To Evaluate the Impact of Uncontrolled HbA1C Levels on Hearing in Patients of Type 1 Diabetes Mellitus.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Audiological profile of patients with type 2 diabetes mellitus.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2024Article
- Article
- Cardiometabolic diseases according to the type and degree of hearing loss in noise-exposed workers.Annals of occupational and environmental medicine · 2024Article
- Association of TyG index with hypertension in Chinese adults: the China Health Examination Collaborative Study (CHEC Study).Asia Pacific journal of clinical nutrition · 2023Article
- Estimated Glomerular Filtration Rate and Hearing Impairment in Japan: A Longitudinal Analysis Using Large-Scale Occupational Health Check-Up Data.International journal of environmental research and public health · 2022Article
- Association between serum uric acid and obesity in Chinese adults: a 9-year longitudinal data analysis.BMJ open · 2021Article
- The Association Between Glycolyzed Hemoglobin A1c and Hearing Loss in Diabetic Patients.Cureus · 2020Article
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Authors and funding
12 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to determine whether haemoglobin A1c (HbA1c) level is associated with the incidence of hearing impairment accounting for smoking status and diabetic condition at baseline.
methodsParticipants were 131 689 men and 71 286 women aged 30-65 years and free of hearing impairment at baseline (2008) who attended Japanese occupational annual health check-ups from 2008 to 2015. We defined low-frequency hearing impairment at a hearing threshold >30 dB at 1 kHz and high frequency at >40 dB at 4 kHz in the better ear in pure-tone audiometric tests. HbA1c was categorised into seven categories. The association between HbA1c and hearing impairment was assessed using the Cox proportional hazards model.
resultsOn 5 years mean follow-up, high HbA1c was associated with high-frequency hearing impairment. In non-smokers, HbA1c≥8.0% was associated with high-frequency hearing impairment, with a multivariable HR (95% CI) compared with HbA1c 5.0%-5.4% of 1.46 (1.10 to 1.94) in men and 2.15 (1.13 to 4.10) in women. There was no significant association between HbA1c and hearing impairment in smokers. A J-shaped association between HbA1c and high-frequency hearing impairment was observed for participants with diabetes at baseline. HbA1c was not associated with low-frequency hearing impairment among any participants.
conclusionsHbA1c ≥8.0% of non-smokers and ≥7.3% of participants with diabetes was associated with high-frequency hearing impairment. These findings indicate that appropriate glycaemic control may prevent diabetic-related hearing impairment.
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