Evidence map›Paper›PMID 30224050›Full record

ArticleBiophysical journal2018

Water Distribution within Wild-Type NRas Protein and Q61 Mutants during Unrestrained QM/MM Dynamics.

Ruth H Tichauer, Gilles Favre, Stéphanie Cabantous, Georges Landa, Anne Hemeryck, Marie Brut

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Isomer-sourced structure iteration methods forComputational and structural biotechnology journal · 2024
    Article
  3. Mechanism-Based Redesign of GAP to Activate Oncogenic Ras.Journal of the American Chemical Society · 2023
    Article
  4. Review
  5. Dynamic regulation of RAS and RAS signaling.The Biochemical journal · 2023
    Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ruth H TichauerLAAS-CNRS, Université de Toulouse, CNRS, UPS, Toulouse, France.
Gilles FavreCancer Research Center of Toulouse, INSERM U1037, Toulouse, France; Université de Toulouse, Toulouse, France.
Stéphanie CabantousCancer Research Center of Toulouse, INSERM U1037, Toulouse, France; Université de Toulouse, Toulouse, France.
Georges LandaLAAS-CNRS, Université de Toulouse, CNRS, UPS, Toulouse, France.
Anne HemeryckLAAS-CNRS, Université de Toulouse, CNRS, UPS, Toulouse, France.
Marie BrutLAAS-CNRS, Université de Toulouse, CNRS, UPS, Toulouse, France. Electronic address: marie.brut@laas.fr.
Centre National de la Recherche Scientifique · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Point mutations in p21

Indexed as

Molecular Dynamics SimulationBinding SitesCatalytic DomainGlutamineGTP PhosphohydrolasesGuanosine TriphosphateHumansHydrogen BondingHydrolysisMembrane ProteinsMutant ProteinsMutationProtein ConformationWaterGlutamineGTP PhosphohydrolasesGuanosine TriphosphateMembrane ProteinsMutant ProteinsNRAS protein, humanWater

Identifiers

PMID30224050
PMCPMC6260220
OpenAlexW2889216843

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.