ReviewMicrobiome2018
Prokaryotic horizontal gene transfer within the human holobiont: ecological-evolutionary inferences, implications and possibilities.
Review in Microbiome, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed.
- Microbial interactions as the key to understanding and controlling environmental spread of antibiotic resistance genes.npj antimicrobials and resistance · 2025Article
- Article
- 4CAC: 4-class classifier of metagenome contigs using machine learning and assembly graphs.Nucleic acids research · 2024Article
- The Potential Harmful Effects of Genetically Engineered Microorganisms (GEMs) on the Intestinal Microbiome and Public Health.Microorganisms · 2024Review
- Detecting horizontal gene transfer among microbiota: an innovative pipeline for identifying co-shared genes within the mobilome through advanced comparative analysis.Microbiology spectrum · 2024Article
- Establishment and perturbation of human gut microbiome: common trends and variations between Indian and global populations.Gut microbiome (Cambridge, England) · 2024Review
- Methionine-producing tumor micro(be) environment fuels growth of solid tumors.Cellular oncology (Dordrecht, Netherlands) · 2023Article
- Mutualistic interplay between bacteriophages and bacteria in the human gut.Nature reviews. Microbiology · 2022Review
- Nutrition or nature: using elementary flux modes to disentangle the complex forces shaping prokaryote pan-genomes.BMC ecology and evolution · 2022Article
- Multilocus Sequence Typing and Virulence Potential ofMicrobiology spectrum · 2022Article
- The Spread of Antibiotic Resistance Genes In Vivo Model.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022Review
- Gain and loss of antibiotic resistant genes in multidrug resistant bacteria: One Health perspective.Journal of microbiology (Seoul, Korea) · 2021Review
- Antibiotic resistance in the environment: a critical insight on its occurrence, fate, and eco-toxicity.Environmental science and pollution research international · 2021Review
- The gut microbiome: a key player in the complexity of amyotrophic lateral sclerosis (ALS).BMC medicine · 2021Review
- mMGE: a database for human metagenomic extrachromosomal mobile genetic elements.Nucleic acids research · 2021Article
- Antimicrobial resistance in enteric bacteria: current state and next-generation solutions.Gut microbes · 2020Review
- Experimental approaches to tracking mobile genetic elements in microbial communities.FEMS microbiology reviews · 2020Review
- Microbial biogeography and ecology of the mouth and implications for periodontal diseases.Periodontology 2000 · 2020Review
- The Role of Constructive Neutral Evolution in the Development of Complexity from Symbioses: A Microbe-Centric View.Results and problems in cell differentiation · 2020Article
- A Microbial Community Ecology Perspective on the Gut-Microbiome-Brain Axis.Frontiers in endocrinology · 2020Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ubiquity of horizontal gene transfer in the living world, especially among prokaryotes, raises interesting and important scientific questions regarding its effects on the human holobiont i.e., the human and its resident bacterial communities considered together as a unit of selection. Specifically, it would be interesting to determine how particular gene transfer events have influenced holobiont phenotypes in particular ecological niches and, conversely, how specific holobiont phenotypes have influenced gene transfer events. In this synthetic review, we list some notable and recent discoveries of horizontal gene transfer among the prokaryotic component of the human microbiota, and analyze their potential impact on the holobiont from an ecological-evolutionary viewpoint. Finally, the human-Helicobacter pylori association is presented as an illustration of these considerations, followed by a delineation of unresolved questions and avenues for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.