Evidence map›Paper›PMID 30223870›Full record

ArticleTrials2018

Reducing disability via a family centered intervention for acutely ill persons with Alzheimer's disease and related dementias: protocol of a cluster-randomized controlled trial (Fam-FFC study).

Marie Boltz, Ashley Kuzmik, Barbara Resnick, Rebecca Trotta, Jacqueline Mogle, Rhonda BeLue, Douglas Leslie, James E Galvin

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03046121 (Reducing Disability Via a Family-centered Intervention for Acutely-ill Persons With Alzheimer's Disease and Related Dementias), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03046121 nacompletednot on this map

Reducing Disability Via a Family-centered Intervention for Acutely-ill Persons With Alzheimer's Disease and Related Dementias

TypeinterventionalSponsorPenn State UniversityRan2017 to 2023Enrolled461ConditionsAlzheimer DiseaseArmsFamily-centered Function-focused Care (Fam-FFC)
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Pain Incidence, Treatment, and Associated Symptoms in Hospitalized Persons with Dementia.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2021
    Trial
  7. Trial
  8. Article
  9. Dementia Care Partner Health Literacy as a Mediator Between Education and Burden at Hospital Discharge.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The Association of Cognitive Impairment With Depressive Symptoms, Function, and Pain in Hospitalized Older Patients With Dementia.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2023
    Article
  16. A pilot study testing the iOS UB-CAM delirium app.Journal of the American Geriatrics Society · 2023
    Article
  17. Article
  18. Delirium Mediates Incidence of Hospital-Associated Disability Among Older Adults.Journal of the American Medical Directors Association · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Marie BoltzThe Pennsylvania State University, College of Nursing, 306 Nursing Sciences Building, University Park, PA, 16802, USA. mpb40@psu.edu.ORCID http://orcid.org/0000-0003-1133-2249
Ashley KuzmikThe Pennsylvania State University, College of Nursing, 306 Nursing Sciences Building, University Park, PA, 16802, USA.
Barbara ResnickUniversity of Maryland School of Nursing, Baltimore, MD, USA.
Rebecca TrottaHospital of the University of Pennsylvania, Philadelphia, PA, USA.
Jacqueline MogleThe Pennsylvania State University, College of Nursing, 306 Nursing Sciences Building, University Park, PA, 16802, USA.
Rhonda BeLueSt. Louis University, St. Louis, MO, USA.
Douglas LeslieThe Pennsylvania State University, College of Nursing, 306 Nursing Sciences Building, University Park, PA, 16802, USA.
James E GalvinFlorida Atlantic University, Boca Raton, FL, USA.
Pennsylvania State University · USFlorida Atlantic University · USHospital of the University of Pennsylvania · USSaint Louis University · USUniversity of Maryland, Baltimore · US

Funding

Reducing Disability via a Family-centered Intervention for Acutely-ill Persons with Alzheimer's Disease and Related DementiasR01AG054425 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI BOLTZ, MARIE · 2017 to 2021
$2.8M
Testing the Efficacy of FFC-AC-EIT in Patients with Alzheimers Disease and Related DementiasR01AG065338 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI BOLTZ, MARIE, RESNICK, BARBARA · 2020 to 2024
$2.4M
NIA NIH HHS R01 AG054425NIA NIH HHS R01AG054425NIA NIH HHS R01 AG065338
6 · The paper itself

Abstract

backgroundHospitalized older persons with Alzheimer's disease and related dementias are at greater risk for functional decline and increased care dependency after discharge due to a combination of intrinsic factors, environmental, policy, and care practices that restrict physical and cognitive activity, lack of family involvement and limited staff knowledge of dementia care. We have developed a theory-based intervention, Family centered Function-focused Care, that incorporates an educational empowerment model for family caregivers (FCGs) provided within a social-ecological framework to promote specialized care to patients with dementia during hospitalization and the 60-day post-acute period. Primary aims are to test the efficacy of the intervention in improving physical and cognitive recovery in hospitalized persons living with Alzheimer's disease and related dementias (ADRD) and improving FCG preparedness and experiences.

methodWe will implement Family centered Function-focused Care in a cluster-randomized trial of 438 patient/FCG dyads in six hospital units randomized within three hospitals. We hypothesize that patients who receive the intervention will demonstrate better physical function, less delirium occurrence and severity, neuropsychiatric symptoms, and depression compared to those in the control condition (Education-only). We also hypothesize that FCGs enrolled in Family centered Function-focused Care will experience increased preparedness for caregiving, and less strain, burden, and desire to institutionalize, as compared to FCGs the control group. We will also examine the costs and relative cost savings associated with the intervention and will evaluate the cultural appropriateness of Family centered Function-focused Care for families from diverse backgrounds. DISCUSSION: Our theory-based intervention makes use of real-world applicable approaches in a novel and innovative way to change the paradigm of how we currently look at acute care and post-acute transitions in persons with ADRD.

trial registrationClinicalTrials.gov, ID: NCT03046121 . Registered on 8 February 2017.

Indexed as

Health Knowledge, Attitudes, PracticePower, PsychologicalAdaptation, PsychologicalAgedAlzheimer DiseaseCaregiversCognitionCost of IllnessFamily RelationsFemaleHumansMaleMemoryMulticenter Studies as TopicNew EnglandPatient Care PlanningDementiaFamily engagementFunctional recoveryHospitalizationPost-acute

Identifiers

PMID30223870
PMCPMC6142366
OpenAlexW2889904054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.