Evidence map›Paper›PMID 30223828›Full record

Observational studyCardiovascular ultrasound2018

Comprehensive assessment of left ventricular myocardial function by two-dimensional speckle-tracking echocardiography.

Vicente Mora, Ildefonso Roldán, Elena Romero, Diana Romero, Javier Bertolín, Natalia Ugalde, Carmen Pérez-Olivares, Melisa Rodriguez-Israel, Jana Pérez-Gozalbo, Jorge A Lowenstein

Abstract readObservational Study
In one paragraph

Observational study in Cardiovascular ultrasound, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vicente MoraCardiology Department, Hospital Dr Peset, Valencia, Spain. vmoral@comv.es.ORCID http://orcid.org/0000-0002-5864-6854
Ildefonso RoldánCardiology Department, Hospital Dr Peset, Valencia, Spain.
Elena RomeroCardiology Department, Hospital Dr Peset, Valencia, Spain.
Diana RomeroCardiodiagnosis Department Medical Research of Buenos Aires, Buenos Aires, Argentina.
Javier BertolínCardiology Department, Hospital Dr Peset, Valencia, Spain.
Natalia UgaldeCardiodiagnosis Department Medical Research of Buenos Aires, Buenos Aires, Argentina.
Carmen Pérez-OlivaresCardiology Department, Hospital Dr Peset, Valencia, Spain.
Melisa Rodriguez-IsraelCardiodiagnosis Department Medical Research of Buenos Aires, Buenos Aires, Argentina.
Jana Pérez-GozalboCardiology Department, Hospital Dr Peset, Valencia, Spain.
Jorge A LowensteinCardiodiagnosis Department Medical Research of Buenos Aires, Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft ventricular ejection fraction (LVEF) results from the combined action of longitudinal and circumferential contraction, radial thickening, and basal and apical rotation. The study of these parameters together may lead to an accurate assessment of the cardiac function.

methodsNinety healthy volunteers, categorized by gender and age (≤ 55 and >  55 years), were evaluated using two-dimensional speckle tracking echocardiography. Transversal views of the left ventricle (LV) were obtained to calculate circumferential strain and left ventricular twist, while three apical views were obtained to determine longitudinal strain (LS) and mitral annular plane systolic excursion (MAPSE). We established the integral myocardial function of the LV according to: 1. The Combined Deformation Parameter (CDP), which includes Deformation Product (DP) - Twist x LS (° x %) - and Deformation Index (DefI) -Twist / LS (° / %)-; and 2. the Torsion Index (TorI): Twist / MAPSE (° / cm).

resultsThe mean age of our patients was 50.3 ± 11.1 years. CDP did not vary with gender or age. The average DP was - 432 ± 172 ° x %, and the average DefI was - 0.96 ± 0.36 ° / %. DP provides information about myocardial function (normal, pseudonormal, depressed), and the DefI quotient indicates which component (s) is/are affected in cases of abnormality. TorI was higher in volunteers over 55 years (16.5 ± 15.2 vs 13.1 ± 5.0 °/cm, p = 0.003), but did not vary with gender.

conclusionsThe proposed parameters integrate values of twisting and longitudinal shortening. They allow a complete physiological assessment of cardiac systolic function, and could be used for the early detection and characterization of its alteration.

Indexed as

EchocardiographyFemaleHealthy VolunteersHeart VentriclesHumansMaleMiddle AgedProspective StudiesStroke VolumeSystoleVentricular Function, LeftDeformation imagingMyocardial strainSpeckle trackingVentricular functionVentricular torsion

Identifiers

PMID30223828
PMCPMC6142420

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.