Evidence map›Paper›PMID 30223488›Full record

ArticleNutrients2018

Bergamot Polyphenol Fraction Exerts Effects on Bone Biology by Activating ERK 1/2 and Wnt/β-Catenin Pathway and Regulating Bone Biomarkers in Bone Cell Cultures.

Arturo Pujia, Cristina Russo, Samantha Maurotti, Roberta Pujia, Vincenzo Mollace, Stefano Romeo, Tiziana Montalcini

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Bergamot (Foods (Basel, Switzerland) · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Arturo PujiaDepartment of Medical and Surgical Science, University Magna Grecia, 88100 Catanzaro, Italy. pujia@unicz.it.
Cristina RussoDepartment of Medical and Surgical Science, University Magna Grecia, 88100 Catanzaro, Italy. crusso@unicz.it.
Samantha MaurottiDepartment of Medical and Surgical Science, University Magna Grecia, 88100 Catanzaro, Italy. samabiotec@yahoo.it.
Roberta PujiaDepartment of Health Science, University Magna Grecia, 88100 Catanzaro, Italy. robertapuj@gmail.com.
Vincenzo MollaceDepartment of Health Science, University Magna Grecia, 88100 Catanzaro, Italy. mollace@unicz.it.
Stefano RomeoDepartment of Medical and Surgical Science, University Magna Grecia, 88100 Catanzaro, Italy. romeo@unicz.it.
Tiziana MontalciniDepartment of Clinical and Experimental Medicine, Nutrition Unit, University Magna Grecia, 88100 Catanzaro, Italy. tmontalcini@unicz.it.
Magna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidemiological studies show that fruit consumption may modulate bone mineral density. However, data regarding the effect of the

Indexed as

Citrusbeta CateninBiomarkersBone RemodelingCell DifferentiationCell LineCollagen Type ICore Binding Factor Alpha 1 SubunitEnzyme ActivationFruitHumansMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3OsteoblastsPhosphorylationPlant Extractsbeta CateninBiomarkersCollagen Type ICore Binding Factor Alpha 1 SubunitCTNNB1 protein, humanMAPK1 protein, humanMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Plant ExtractsPolyphenolsRANK LigandRUNX2 protein, humanTNFSF11 protein, humanBergamotbone cellscitrus fruitsosteoporosispolyphenolsSaos-2β-catenin

Identifiers

PMID30223488
PMCPMC6163325
OpenAlexW2890163371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.