Evidence map›Paper›PMID 30222979›Full record

ArticleToxicology and applied pharmacology2018

Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.

John T Szilagyi, Karma C Fussell, Yun Wang, Yi-Hua Jan, Vladimir Mishin, Jason R Richardson, Diane E Heck, Shaojun Yang, Lauren M Aleksunes, Debra L Laskin and 1 more

Open access · greenAbstract read
In one paragraph

Article in Toxicology and applied pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Roles of Ferredoxin-NADPAntioxidants (Basel, Switzerland) · 2022
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

John T SzilagyiDepartment of Environmental and Occupational Health, Rutgers University School of Public Health, Piscataway, NJ 08854, United States.
Karma C FussellDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, United States.
Yun WangDepartment of Environmental and Occupational Health, Rutgers University School of Public Health, Piscataway, NJ 08854, United States.
Yi-Hua JanDepartment of Environmental and Occupational Health, Rutgers University School of Public Health, Piscataway, NJ 08854, United States.
Vladimir MishinDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, United States.
Jason R RichardsonDepartment of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, United States.
Diane E HeckDepartment of Environmental Health Science, New York Medical College, Valhalla, NY 10595, United States.
Shaojun YangDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, United States.
Lauren M AleksunesDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, United States.
Debra L LaskinDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, United States.
Jeffrey D LaskinDepartment of Environmental and Occupational Health, Rutgers University School of Public Health, Piscataway, NJ 08854, United States. Electronic address: jlaskin@eohsi.rutgers.edu.
Rutgers, The State University of New Jersey · USNew York Medical College · USNortheast Ohio Medical University · US

Funding

UMDNJ/Rutgers University CounterACT Research Center of ExcellenceU54AR055073 · NIAMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI LASKIN, JEFFREY D · 2006 to 2024
$71.4M
Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI PANOS G. GEORGOPOULOS · 1988 to 2026
$47.4M
TRAINING IN EVIRONMENTAL TOXICOLOGYT32ES007148 · NIEHS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI Lauren M Aleksunes · 1987 to 2026
$11.4M
ACTIVATED MACROPHAGES AND OZONE TOXICITYR01ES004738 · NIEHS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI Debra L Laskin · 1989 to 2026
$9.0M
Advanced Development of Drugs to Mitigate Parathion IntoxicationU01NS108956 · NINDS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI LASKIN, JEFFREY D, RICHARDSON, JASON R · 2018 to 2022
$3.9M
"Development of Drugs to Mitigate Parathion Intoxication"R21NS072097 · NINDS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI LASKIN, JEFFREY D · 2010 to 2012
$857k
NIAMS NIH HHS U54 AR055073NIEHS NIH HHS P30 ES005022NIEHS NIH HHS R01 ES004738NIEHS NIH HHS T32 ES007148NINDS NIH HHS R21 NS072097NINDS NIH HHS U01 NS108956
6 · The paper itself

Abstract

NADH cytochrome b

Indexed as

BenzoquinonesCytochrome-B(5) ReductaseFree RadicalsHumansKineticsMicrosomes, LiverNADPNitrofurantoinOxidation-ReductionOxygen ConsumptionReactive Oxygen SpeciesRecombinant ProteinsBenzoquinonesCytochrome-B(5) ReductaseFree RadicalsNADPNitrofurantoinquinoneReactive Oxygen SpeciesRecombinant ProteinsCytochrome b5Free radicalsReactive oxygen speciesRedox cycling

Identifiers

PMID30222979
PMCPMC6528659
OpenAlexW2889810336

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.