Evidence map›Paper›PMID 30222913›Full record

ArticleBrain and behavior2018

Thirty-day recurrence after ischemic stroke or TIA.

Andrej Netland Khanevski, Anna Therese Bjerkreim, Vojtech Novotny, Halvor Naess, Lars Thomassen, Nicola Logallo, Christopher E Kvistad

Abstract read
In one paragraph

Article in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. In-house Stroke: Are We Concerned Enough?Annals of Indian Academy of Neurology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrej Netland KhanevskiDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0002-6371-628X
Anna Therese BjerkreimDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0002-3096-8595
Vojtech NovotnyDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0002-9137-3894
Halvor NaessDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Lars ThomassenDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Nicola LogalloDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Christopher E KvistadDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncidence of recurrent stroke is highest within 30 days after the initial ischemic stroke (IS) or TIA, but knowledge about early recurrence is lacking. We aimed to identify etiological groups with highest risk of early recurrence and assess how the TOAST classification identified index stroke etiology.

methodsMedical records of 1874 IS and TIA patients in the Bergen NORSTROKE registry were retrospectively reviewed for identification of recurrent IS or TIA within 30 days after index IS or TIA. Stroke etiology was determined by review of electronical medical journals. Logistic regression was used to calculate odds ratios (OR) for 30-day recurrence.

resultsThirty-three patients (1.8%) were readmitted with recurrent IS or TIA within 30 days after index stroke. By using TOAST, 12 patients were initially classified with stroke of unknown etiology (SUE). Etiologies behind recurrent IS or TIA were after the recurrent episode identified as extracranial large artery atherosclerosis (LAA) in 14 patients (42.4%), intracranial arterial pathology in seven patients (21.2%), active malignancy in six patients (18.2%), and cardio embolism in four patients (12.1%). Small vessel occlusion and SUE were the causes in one patient each. Logistic regression showed that patients with stroke of other determined etiology (SOE) and LAA had increased risk of 30-day recurrence (OR = 9.72, 95% CI 1.84-51.3, p < 0.01 and OR = 4.36, 95% CI 2.01-9.47, p < 0.01, respectively).

conclusionPatients with LAA and SOE had increased risk of recurrent IS or TIA within 30 days. TOAST was inadequate at identifying exact etiologies behind recurrent stroke at index event.

Indexed as

AgedAged, 80 and overBrain IschemiaFemaleHumansIschemic Attack, TransientMaleMiddle AgedRecurrenceRetrospective StudiesRisk FactorsStrokecerebrovascular diseaseischemic strokereadmissionstroke etiologystroke recurrence

Identifiers

PMID30222913
PMCPMC6192402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.