ArticlePloS one2018
Comparison of strain elastography, point shear wave elastography using acoustic radiation force impulse imaging and 2D-shear wave elastography for the differentiation of thyroid nodules.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- SuperSonic shear imaging for the differentiation between benign and malignant thyroid nodules: a meta-analysis.Journal of endocrinological investigation · 2022Pooled it
- US-Elastography With Different Techniques for Thyroid Nodule Characterization: Systematic Review and Meta-analysis.Frontiers in oncology · 2022Pooled it
- Accuracy of real-time shear wave elastography in staging hepatic fibrosis: a meta-analysis.BMC medical imaging · 2020Pooled it
- Use of strain and shear wave elastography in the ultrasonographic evaluation of the intermediate patellar ligament in horses: comparison and consistency of data.Frontiers in veterinary science · 2026Article
- Enhancing diagnostic precision for thyroid C-TIRADS category 4 nodules: a hybrid deep learning and machine learning model integrating grayscale and elastographic ultrasound features.Quantitative imaging in medicine and surgery · 2025Article
- Ultrasonographic Elastography of the Spleen for Diagnosing Neoplastic Myeloproliferation: Identifying the Most Promising Methods-A Systematic Review.Journal of clinical medicine · 2025Review
- Role of Ultrasound Elastography and Contrast-Enhanced Ultrasound (CEUS) in Diagnosis and Management of Malignant Thyroid Nodules-An Update.Diagnostics (Basel, Switzerland) · 2025Review
- Diagnostic value of ultrasound elastography and conventional ultrasound for thyroid nodules: a meta-analysis.Quantitative imaging in medicine and surgery · 2023Article
- Role of Preoperative Ultrasound Shear-Wave Elastography and Radiofrequency-Based Arterial Wall Tracking in Assessing the Vulnerability of Carotid Plaques: Preliminary Results.Diagnostics (Basel, Switzerland) · 2023Article
- Elastography of the thyroid nodule, cut-off points between benign and malignant lesions for strain, 2D shear wave real time and point shear wave: a correlation with pathology, ACR TIRADS and Alpha Score.Frontiers in endocrinology · 2023Article
- Evaluation of thyroid nodules by shear wave elastography: a review of current knowledge.Journal of endocrinological investigation · 2021Review
- Role of elastography strain ratio and TIRADS score in predicting malignant thyroid nodule.Archives of endocrinology and metabolism · 2021Article
- The current value of quantitative shear wave sonoelastography in parotid gland tumors.Gland surgery · 2021Article
- Clinical Value of Shear Wave Elastography Color Scores in Classifying Thyroid Nodules.International journal of general medicine · 2021Article
- Elastography for the diagnosis of high-suspicion thyroid nodules based on the 2015 American Thyroid Association guidelines: a multicenter study.BMC endocrine disorders · 2020Article
- Two-Dimensional Shear Wave Elastography of Normal Soft Tissue Organs in Adult Beagle Dogs; Interobserver Agreement and Sources of Variability.Frontiers in bioengineering and biotechnology · 2020Article
- Ultrasound elastography in the evaluation of thyroid nodules: evolution of a promising diagnostic tool for predicting the risk of malignancy.Radiologia brasileiraReview
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of the study was to compare three different elastography methods, namely Strain Elastography (SE), Point Shear-Wave Elastography (pSWE) using Acoustic Radiation Force Impulse (ARFI)-Imaging and 2D-Shear Wave Elastography (2D-SWE), in the same study population for the differentiation of thyroid nodules. MATERIALS AND
methodsAll patients received a conventional ultrasound scan, SE and 2D-SWE, and all patients except for two received ARFI-Imaging. Cytology/histology of thyroid nodules was used as a reference method. SE measures the relative stiffness within the region of interest (ROI) using the surrounding tissue as reference tissue. ARFI mechanically excites the tissue at the ROI using acoustic pulses to generate localized tissue displacements. 2D-SWE measures tissue elasticity using the velocity of many shear waves as they propagate through the tissue.
results84 nodules (73 benign and 11 malignant) in 62 patients were analyzed. Sensitivity, specificity and NPV of SE were 73%, 70% and 94%, respectively. Sensitivity, specificity and NPV of ARFI and 2D-SWE were 90%, 79%, 98% and 73%, 67%, 94% respectively, using a cut-off value of 1.98m/s for ARFI and 2.65m/s (21.07kPa) for 2D-SWE. The AUROC (Area under the Receiver Operating Characteristic) of SE, ARFI and 2D-SWE for the diagnosis of malignant thyroid nodules were 52%, 86% and 71%, respectively. A significant difference in AUROC was found between SE and ARFI (p = 0.008), while no significant difference was found between ARFI and SWE (86% vs. 71%, p = 0.31), or SWE and SE (71% vs. 52%, p = 0.26).
conclusionpSWE using ARFI and 2D-SWE showed comparable results for the differentiation of thyroid nodules. ARFI was superior to elastography using SE.
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