Evidence map›Paper›PMID 30222591›Full record

ArticleAging2018

The etiological effect of a new low-frequency

Xiaoling Li, Xiaoquan Zhu, Wandong Zhang, Fan Yang, Juan Hui, Jiping Tan, Haiqun Xie, Dantao Peng, Lihua Ma, Lianqi Cui and 10 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. AnFrontiers in genetics · 2024
    Article
  3. Prognostic value of plasma Aβ1-40 for Alzheimer's disease.American journal of translational research · 2024
    Article
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 12 institutions in 2 countries.

Xiaoling LiGraduate School of Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100001, P.R.China.
Xiaoquan ZhuThe MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, P.R.China.
Wandong ZhangDepartment of Pathology and Laboratory of Medicine, Faculty of Medicine, University of Ottawa, Ottawa, K1H 8M5, Canada.
Fan YangThe MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, P.R.China.
Juan HuiThe MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, P.R.China.
Jiping TanDepartment of Geriatric Neurology, Chinese PLA General Hospital, Beijing, 100730, P.R.China.
Haiqun XieDepartment of Neurology, Affiliated Foshan Hospital of Sun Yat-sen University, Foshan, 528000, P.R.China.
Dantao PengChina-Japan Friendship Hospital, Beijing, 100029, P.R.China.
Lihua Ma253 Hospital of PLA, Huhehot,, 010051, P.R.China.
Lianqi CuiDepartment of Neurology, 401 Hospital of PLA, Qingdao, Shandong 266100, P.R.China.
Shouzi ZhangDepartment of Neurology of Beijing Geriatric Hospital, Beijing, 100095, P.R.China.
Zeping LvNational Rehabilitation Aids Research Center, Ministry of Civil Affairs, Beijing, 100176, P.R.China.
Liang SunThe MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, P.R.China.
Huiping YuanThe MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, P.R.China.
Qi ZhouThe MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, P.R.China.
Luning WangDepartment of Geriatric Neurology, Chinese PLA General Hospital, Beijing, 100730, P.R.China.
Shige QiNational Center for Chronic and Non-communicable Diseae Control and Prevention, Chinease CDC, Beijing, 100050, P.R.China.
Zhihui WangNational Center for Chronic and Non-communicable Diseae Control and Prevention, Chinease CDC, Beijing, 100050, P.R.China.
Caiyou HuDepartment of Neurology, Jiangbin Hospital, Guangxi Zhuang Autonomous Region, Nanning, 530021, P.R.China.
Ze YangGraduate School of Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100001, P.R.China.
Beijing Hospital · CNChinese PLA General Hospital · CNNational Center for Chronic and Noncommunicable Disease Control and Prevention · CN82th Hospital of Pla · CNBeijing Geriatric Hospital · CNChina-Japan Friendship Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNFoshan Hospital of TCM · CNNational Research Center for Rehabilitation Technical Aids · CNPeople's Liberation Army 401 Hospital · CNThe People's Hospital of Guangxi Zhuang Autonomous Region · CNUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Latent genetic variations of cholesterol metabolism-related genes in late-onset Alzheimer's disease, especially, as well as in mild cognitive impairment pathogenesis are still to be studied extensively. Thus, we performed the targeted-sequencing of 12 nuclear receptor genes plus

Indexed as

Polymorphism, Single NucleotideAlzheimer DiseaseAmyloid beta-PeptidesApolipoproteins ECholesterolCognitive DysfunctionEstrogen Receptor alphaFemaleHumansMaleAmyloid beta-PeptidesApolipoproteins ECholesterolESR1 protein, humanEstrogen Receptor alphaADAβcholesterolESR1MCI

Identifiers

PMID30222591
PMCPMC6188501
OpenAlexW2889907208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.