Evidence map›Paper›PMID 30222360›Full record

ArticleMolecular pharmaceutics2018

Improved Cancer Immunochemotherapy via Optimal Co-delivery of Chemotherapeutic and Immunomodulatory Agents.

Yichao Chen, Jingjing Sun, Yixian Huang, Binfeng Lu, Song Li

Abstract read
In one paragraph

Article in Molecular pharmaceutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yichao ChenCenter for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.
Jingjing SunCenter for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.ORCID 0000-0002-6230-1015
Yixian HuangCenter for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.
Binfeng LuDepartment of Immunology , University of Pittsburgh School of Medicine , 200 Lothrop Street , Pittsburgh , Pennsylvania 15261 , United States.
Song LiCenter for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.
University of Pittsburgh · US

Funding

Immunostimulatory Nanocarrier for Breast Cancer ImmunochemotherapyR01CA219399 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LI, SONG · 2017 to 2021
$2.3M
Study of Interleukin 33 as a new immunotherapy of lung cancerR01CA239716 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LI, SONG, LU, BINFENG · 2019 to 2023
$1.8M
Nanotherapeutics for Synergistic Targeting of Myc in Prostate CancerR01CA223788 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LI, SONG · 2018 to 2022
$1.8M
Targeted Combination Therapy for Breast CancerR01CA174305 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LI, SONG · 2014 to 2018
$1.6M
NCI NIH HHS R01 CA174305NCI NIH HHS R01 CA219399NCI NIH HHS R01 CA223788NCI NIH HHS R01 CA239716
6 · The paper itself

Abstract

It is highly demanded and still a big challenge to develop an effective formulation for immunochemotherapy against advanced tumors. We have previously reported a PEG-NLG-based immunostimulatory nanocarrier (PEG

Indexed as

AnimalsAntineoplastic Combined Chemotherapy ProtocolsCell Line, TumorDrug CarriersFemaleImidazolesImmunologic FactorsImmunotherapyIsoindolesMammary Neoplasms, ExperimentalMiceMice, Inbred BALB CMicellesMyeloid-Derived Suppressor CellsPaclitaxelPolyethylene Glycols1-cyclohexyl-2-(5H-imidazo(5,1-a)isoindol-5-yl)ethanolDrug CarriersImidazolesImmunologic FactorsIsoindolesMicellesPaclitaxelPolyethylene GlycolsSunitinibimmunotherapyindoleamine 2,3-dioxygenase 1myeloid-derived suppressor cellssunitinib

Identifiers

PMID30222360
PMCPMC6452437
OpenAlexW2891140299

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.