ReviewJournal of veterinary internal medicine2018
Clinical utility of currently available biomarkers in inflammatory enteropathies of dogs.
Review in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 86 citations in OpenAlex.
- Proteomics in Gastrointestinal Diseases of Companion Animals: Current State and Knowledge Gaps.Animals : an open access journal from MDPI · 2026Review
- Clinical benefit of faecal microbiota transplantation administered via a single retention enema as an adjunctive treatment in dogs with chronic enteropathy: a randomised controlled trial.The Journal of small animal practice · 2026Article
- An Ecological Framework for Interpreting the Canine Gut Microbiome.Animals : an open access journal from MDPI · 2026Article
- Elastography of the Intestinal Mucosa of Dogs With Chronic Inflammatory Enteropathy.Veterinary medicine international · 2026Article
- Retrospective evaluation of short- and medium-term therapeutic response to different immunosuppressive and dietary approaches in 148 dogs diagnosed with immunosuppressant-responsive enteropathy.Open veterinary journal · 2025Article
- Comparative Analysis of the Fecal Proteome in Two Canine Breeds: Dalmatians and Weimaraners.International journal of molecular sciences · 2025Article
- Liquid Hydrolyzed Fish Protein (Anchovy) in the Canine Diet: A Focus on Gut Fermentation and Fecal Quality.Veterinary sciences · 2025Article
- Properdin, transcortin and HGFAC are novel plasma biomarkers in canine chronic inflammatory enteropathies from active disease to remission.Scientific reports · 2025Article
- Assessment of duodenal villous morphology in canine IBD using magnification endoscopy with water immersion technique (WIT) and image skeletonization.Veterinary research communications · 2025Article
- Markers of Gut Health in Small Animals: Focus on Fatty Acids and Amino Acids as Indicators of Intestinal Functionality and Microbiome Activity.Animals : an open access journal from MDPI · 2025Review
- Coagulation Status Assessment in Dogs with Chronic Enteropathy Using Viscoelastic Point-of-Care Coagulation Monitor.Animals : an open access journal from MDPI · 2025Article
- An extensively hydrolysed protein-based extruded diet in the treatment of dogs with chronic enteropathy and at least one previous diet-trial failure: a pilot uncontrolled open-label study.BMC veterinary research · 2025Article
- Effects of supplemental seaweed extract on antioxidant properties, loose stools, gut microbiota, and its metabolite composition in adult dogs.Journal of animal science · 2025Article
- Correlation of disease markers with clinical, endoscopic, and histologic findings in dogs with chronic gastrointestinal inflammation.Brazilian journal of veterinary medicine · 2025Article
- Article
- Duodenal and colonic mucosal S100A8/A9 (calprotectin) expression is increased and correlates with the severity of select histologic lesions in dogs with chronic inflammatory enteropathy.BMC veterinary research · 2024Article
- Serum D-Lactate Concentrations in Dogs with Inflammatory Bowel Disease.Animals : an open access journal from MDPI · 2024Article
- A Comprehensive Exploration of Therapeutic Strategies in Inflammatory Bowel Diseases: Insights from Human and Animal Studies.Biomedicines · 2024Review
- Monocytes Count, NLR, MLR and PLR in Canine Inflammatory Bowel Disease.Animals : an open access journal from MDPI · 2024Article
- Updating the Classification of Chronic Inflammatory Enteropathies in Dogs.Animals : an open access journal from MDPI · 2024Review
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Chronic inflammatory enteropathies (CIE) in dogs are a group of disorders that are characterized by chronic persistent or recurrent signs of gastrointestinal disease and histologic evidence of mucosal inflammation. These CIEs are classified as either food-responsive, antibiotic-responsive, or immunosuppressant-responsive enteropathy. Patients not clinically responding to immunomodulatory treatment are grouped as nonresponsive enteropathy and dogs with intestinal protein loss as protein-losing enteropathy. Disease-independent clinical scoring systems were established in dogs for assessment of clinical disease severity and patient monitoring during treatment. Histopathologic and routine clinicopathologic findings are usually not able to distinguish the subgroups of CIE. Treatment trials are often lengthy and further diagnostic tests are usually at least minimally invasive. Biomarkers that can aid in defining the presence of disease, site of origin, severity of the disease process, response to treatment, or a combination of these would be clinically useful in dogs with CIE. This article summarizes the following biomarkers that have been evaluated in dogs with CIE during the last decade, and critically evaluates their potential clinical utility in dogs with CIE: functional biomarkers (cobalamin, methylmalonic acid, folate, α
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.