Evidence map›Paper›PMID 30221993›Full record

ArticleCNS oncology2018

Rapid infusion rituximab is well tolerated in patients with primary CNS lymphoma.

Lisa Modelevsky, Richard Tizon, Samantha N Reiss, Marcel Smith, Rachel Garonce, Thomas Kaley

Abstract read
In one paragraph

Article in CNS oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lisa ModelevskyMemorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA.
Richard TizonMemorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA.
Samantha N ReissMemorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA.
Marcel SmithMemorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA.
Rachel GaronceMemorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA.
Thomas KaleyMemorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

aimTo establish the safety and feasibility of rapidly infusing rituximab over 90 min in patients with primary CNS lymphoma (PCNSL). PATIENTS &

methodsWe retrospectively reviewed all patients with PCNSL who received rapid rituximab infusions (RRI) from January 2016 to January 2017. Primary end point was incidence of infusion reactions. RESULTS &

conclusion11 patients received a total of 44 RRIs. Rituximab was dosed at 500 or 750 mg/m

Indexed as

AdultAgedAntineoplastic Agents, ImmunologicalBrain NeoplasmsDose-Response Relationship, DrugFemaleHumansLymphoma, Non-HodgkinMaleMiddle AgedRetrospective StudiesRituximabTreatment OutcomeAntineoplastic Agents, ImmunologicalRituximabneuro-oncologyprimary CNS lymphomarapid infusionrituximab

Identifiers

PMID30221993
PMCPMC6200062

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.