Evidence map›Paper›PMID 30221242›Full record

ArticleBiostatistics & epidemiology2017

Classification of ADNI PET Images via Regularized 3D Functional Data Analysis.

Xuejing Wang, Bin Nan, Ji Zhu, Robert Koeppe, Kirk Frey, Alzheimer’s Disease Neuroimaging Initiative

Open access · bronzeAbstract read
In one paragraph

Article in Biostatistics & epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Histogram-Based Features Selection and Volume of Interest Ranking for Brain PET Image Classification.IEEE journal of translational engineering in health and medicine · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xuejing WangEli Lilly and Company, Indianapolis, IN 46285, USA.
Bin NanDepartment of Biostatistics, University of Michigan, Ann Arbor, MI, 48109 USA.
Ji ZhuDepartment of Statistics, University of Michigan, Ann Arbor, MI, 48109 USA.
Robert KoeppeDepartment of Radiology, University of Michigan, Ann Arbor, MI, 48109 USA.
Kirk FreyDepartment of Radiology, University of Michigan, Ann Arbor, MI, 48109 USA.
Alzheimer’s Disease Neuroimaging Initiative
University of Michigan–Ann Arbor · USEli Lilly (United States) · US

Funding

Project 1U19AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI MICHAEL W WEINER · 2016 to 2026
$226.7M
Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
UC Davis Alzheimer's Disease Core CenterP30AG010129 · NIA · UNIVERSITY OF CALIFORNIA DAVIS · PI DECARLI, CHARLES · 1991 to 2020
$28.3M
High-Dimensional Data Issues in Aging ResearchR01AG036802 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NAN, BIN · 2010 to 2013
$1.1M
"MR Morphometrics and Cognitive Decline Rate in Large-Scale Aging Studies"K01AG030514 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CARMICHAEL, OWEN T. · 2008 to 2012
$495k
NIA NIH HHS K01 AG030514NIA NIH HHS P30 AG010129NIA NIH HHS R01 AG036802NIA NIH HHS U01 AG024904NIA NIH HHS U19 AG024904
6 · The paper itself

Abstract

We propose a penalized Haar wavelet approach for the classification of 3D brain images in the framework of functional data analysis, which treats each entire 3D brain image as a single functional input thus automatically takes into account the spatial correlations of voxel level imaging measures. We validate the proposed approach through extensive simulations and compare its classification performance with other commonly used machine learning methods, which show that the proposed method outperforms other methods in both classification accuracy and identification of the relevant voxels. We then apply the proposed method to the practical classification problems for Alzheimer's disease using PET images obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database to highlight the advantages of our approach.

Indexed as

Classificationelastic netfunctional logistic regressionHaar waveletsPCAPET

Identifiers

PMID30221242
PMCPMC6136436
OpenAlexW2735296299

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.