Evidence map›Paper›PMID 30221222›Full record

ArticleACS omega2018

Self-Calibration Phenomenon for Near-Infrared Clinical Measurements: Theory, Simulation, and Experiments.

Idit Feder, Hamootal Duadi, Ruchira Chakraborty, Dror Fixler

Abstract read
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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  4. Finite Element Modeling of Abdominal Near-Infrared Spectroscopy for Infant Splanchnic Oximetry.International journal for numerical methods in biomedical engineering · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Idit FederFaculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan 5290002, Israel.
Hamootal DuadiFaculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan 5290002, Israel.
Ruchira ChakrabortyFaculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan 5290002, Israel.
Dror FixlerFaculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan 5290002, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An irradiated turbid medium scatters the light in accordance to its optical properties. Near-infrared (NIR) clinical methods, which are based on spectral-dependent absorption, suffer from an inherent error due to spectral-dependent scattering. We present here a unique spatial point, that is, iso-pathlength (IPL) point, on the surface of a tissue at which the intensity of re-emitted light remains constant. This scattering-indifferent point depends solely on the medium geometry. On the basis of this natural phenomenon, we suggest a novel optical method for self-calibrated clinical measurements. We found that the IPL point exists in both cylindrical and semi-infinite tissue geometries (Supporting Information, Video file). Finally, in vivo human finger and mice measurements are used to validate the crossing point between the intensity profiles of two wavelengths. Hence, measurements at the IPL point yield an accurate absorption assessment while eliminating the scattering dependence. This finding can be useful for oxygen saturation determination, NIR spectroscopy, photoplethysmography measurements, and a wide range of optical sensing methods for physiological aims.

Identifiers

PMID30221222
PMCPMC6130783

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.