Evidence map›Paper›PMID 30221218›Full record

ArticleACS omega2018

Combined Adsorption and Covalent Linking of Paclitaxel on Functionalized Nano-Graphene Oxide for Inhibiting Cancer Cells.

Wei Zhuang, Linjiao He, Kai Wang, Bo Ma, Lei Ge, Zhenfu Wang, Jinsha Huang, Jinglan Wu, Qi Zhang, Hanjie Ying

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wei ZhuangState Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, No. 5 Xinmofan Road, Nanjing 210009, China.
Linjiao HeNational Engineering Technique Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering and School of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing 211816, China.
Kai WangFreshwater Fisheries Research Institute of Jiangsu Province, No. 79 Chating East Street, Nanjing 210017, China.
Bo MaNational Engineering Technique Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering and School of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing 211816, China.
Lei GeCentre for Future Materials, University of Southern Queensland, Springfield, Queensland 4300, Australia.
Zhenfu WangNational Engineering Technique Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering and School of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing 211816, China.
Jinsha HuangNational Engineering Technique Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering and School of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing 211816, China.
Jinglan WuNational Engineering Technique Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering and School of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing 211816, China.
Qi ZhangNational Engineering Technique Research Center for Biotechnology, College of Biotechnology and Pharmaceutical Engineering and School of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing 211816, China.
Hanjie YingState Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, No. 5 Xinmofan Road, Nanjing 210009, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing targeted delivery nanosystems for delivering chemotherapeutic anticancer drugs specifically to cancerous tissues with improvement in the specificity of drugs for different cancer cells can result in high therapeutic efficacy and low toxicity in healthy tissues. Herein, we proposed the synthesis of a multifunctional nanodelivery system, folic acid (FA) decorating nanographene oxide (nGO) functionalized with poly(ethylene glycol) (PEG), called pGO-FA, with good biocompatibility and good delivering performance of a hydrophobic water-insoluble anticancer drug of paclitaxel (PTX). 4-br-PEG-NH

Identifiers

PMID30221218
PMCPMC6130789

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.