Evidence map›Paper›PMID 30221128›Full record

ArticleNano energy2018

Study of Long-Term Biocompatibility and Bio-Safety of Implantable Nanogenerators.

Jun Li, Lei Kang, Yanhao Yu, Yin Long, Justin J Jeffery, Weibo Cai, Xudong Wang

Abstract read
In one paragraph

Article in Nano energy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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  16. Ultra-Thin Flexible Encapsulating Materials for Soft Bio-Integrated Electronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jun LiDepartment of Materials Science and Engineering, University of Wisconsin-Madison, WI, 53706, USA.
Lei KangDepartment of Radiology, University of Wisconsin - Madison, WI, 53705, USA.
Yanhao YuDepartment of Materials Science and Engineering, University of Wisconsin-Madison, WI, 53706, USA.
Yin LongDepartment of Materials Science and Engineering, University of Wisconsin-Madison, WI, 53706, USA.
Justin J JefferyUniversity of Wisconsin Carbone Cancer Center, Madison, WI, 53705, USA.
Weibo CaiDepartment of Radiology, University of Wisconsin - Madison, WI, 53705, USA.
Xudong WangDepartment of Materials Science and Engineering, University of Wisconsin-Madison, WI, 53706, USA.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Membranous Nanogenerators for in vivo Bio-mechanical Energy HarvestingR01EB021336 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI WANG, XUDONG · 2016 to 2020
$1.7M
NCI NIH HHS P30 CA014520NIBIB NIH HHS R01 EB021336
6 · The paper itself

Abstract

Implantable nanogenerator (i-NG) has shown great promises for enabling self-powered implantable medical devices (IMDs). One essential requirement for practical i-NG applications is its long-term bio-compatibility and bio-safety. This paper presents a systematic study of polydimethylsiloxane (PDMS) and PDMS/Parylene-C packaged Polyvinylidene fluoride (PVDF) NGs implanted inside female ICR (Institute of Cancer Research) mice for up to six months. The PVDF NG had a stable in vitro output of 0.3 V when bended for 7200 cycles and an in vivo output of 0.1V under stretching. Multiple advanced imaging techniques, including computed tomography (CT), ultrasound, and photoacoustic were used to characterize the embedded i-NGs

Indexed as

BiocompatibilityBiomechanical energy harvestingImplantable NanogeneratorIn Vivo imagingPVDF

Identifiers

PMID30221128
PMCPMC6135531

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.