Evidence map›Paper›PMID 30221031›Full record

ArticleACS catalysis2018

Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to Hydroxyaldehydes.

Raquel Roldán, Karel Hernandez, Jesús Joglar, Jordi Bujons, Teodor Parella, Israel Sánchez-Moreno, Virgil Hélaine, Marielle Lemaire, Christine Guérard-Hélaine, Wolf-Dieter Fessner and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in ACS catalysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Streptavidin-Hosted Organocatalytic Aldol Addition.Molecules (Basel, Switzerland) · 2020
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Raquel RoldánBiological Chemistry Department, Instituto de Química Avanzada de Cataluña IQAC-CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain.
Karel HernandezBiological Chemistry Department, Instituto de Química Avanzada de Cataluña IQAC-CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain.
Jesús JoglarBiological Chemistry Department, Instituto de Química Avanzada de Cataluña IQAC-CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain.
Jordi BujonsBiological Chemistry Department, Instituto de Química Avanzada de Cataluña IQAC-CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain.
Teodor ParellaServei de Ressonància Magnètica Nuclear, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.
Israel Sánchez-MorenoUniversity Clermont Auvergne, CNRS, SIGMA Clermont, Institut de Chimie de Clermont-Ferrand, 63000 Clermont-Ferrand, France.
Virgil HélaineUniversity Clermont Auvergne, CNRS, SIGMA Clermont, Institut de Chimie de Clermont-Ferrand, 63000 Clermont-Ferrand, France.
Marielle LemaireUniversity Clermont Auvergne, CNRS, SIGMA Clermont, Institut de Chimie de Clermont-Ferrand, 63000 Clermont-Ferrand, France.
Christine Guérard-HélaineUniversity Clermont Auvergne, CNRS, SIGMA Clermont, Institut de Chimie de Clermont-Ferrand, 63000 Clermont-Ferrand, France.
Wolf-Dieter FessnerInstitut für Organische Chemie und Biochemie, Technische Universität Darmstadt, Alarich-Weiss-Str. 4, D-64287 Darmstadt, Germany.
Pere ClapésBiological Chemistry Department, Instituto de Química Avanzada de Cataluña IQAC-CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain.
Institute of Advanced Chemistry of Catalonia · ESCentre National de la Recherche Scientifique · FRTechnische Universität Darmstadt · DEUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asymmetric aldol addition of simple aldehydes and ketones to electrophiles is a cornerstone reaction for the synthesis of unusual sugars and chiral building blocks. We investigated d-fructose-6-phosphate aldolase from

Identifiers

PMID30221031
PMCPMC6135579
OpenAlexW2887676429

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.