ArticleSurgical neurology international2018
Awake craniotomy without sedation in treatment of patients with lesional epilepsy.
Article in Surgical neurology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- An update on tests used for intraoperative monitoring of cognition during awake craniotomy.Acta neurochirurgica · 2024Pooled it
- Feasibility and safety of awake craniotomy in adult patients with drug-resistant focal epilepsy.Epilepsia · 2025Observational
- Awake Craniotomy for the Excision of a Pediatric Cerebral Arteriovenous Malformation for Language Preservation: A Case Description.Journal of personalized medicine · 2025Article
- Awake surgery with mapping-based resection to treat focal epilepsy in eloquent brain areas.Acta neurochirurgica · 2024Article
- Indication and eligibility of glioma patients for awake surgery: A scoping review by a multidisciplinary perspective.Frontiers in oncology · 2022Article
- Awake surgery for lesions near eloquent brain under scalp block and clinical monitoring: experience of single center with limited resources.The Egyptian journal of neurology, psychiatry and neurosurgery · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of awake craniotomy for surgical treatment of epilepsy was applied in surgery of convexital tumors, arteriovenous malformations, some superficial aneurysms, and stereotactic neurosurgery. The aim of this study was to show the advantages of awake craniotomy without sedation, accompanied by intraoperative neurophysiological monitoring in patients with symptomatic epilepsy.
methodsThis article describes the results of surgical treatment in 41 patients with various pathologies; 31 among them suffered from epilepsy.
resultsMost frequently, the pathological foci were located in frontal and parietal lobes nearby eloquent brain areas. Irrespective of damage location, simple partial and complex partial seizures were seen almost with the same frequency. Intraoperative mapping of eloquent cortical areas and subcortical tracts without sedation resulted in total resection of pathological area in 75% of cases with low rate of permanent neurological deficit (two patients). Minor perioperative complications, including the decrease in blood pressure in six patients and intraoperative convulsions in two patients, were handled and did not led to operation termination or anesthesia conversion. Excellent seizures control (Engel 1) was achieved in 80% of patients with available catamnesis.
conclusionThus, the proposed method allows eliminating the complications associated with sedation and provides radical resection of pathological epileptogenic foci with low complication rate.
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